Evidence map›Paper›PMID 40244190›Full record

ArticleInternational journal of molecular sciences2025

Extracellular Vesicle-Derived microRNA Crosstalk Between Equine Chondrocytes and Synoviocytes-An In Vitro Approach.

Catarina I G D Castanheira, James R Anderson, Emily J Clarke, Matthias Hackl, Victoria James, Peter D Clegg, Mandy J Peffers

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. 5EU-Based Tracking of RNA Transfer Through Extracellular Vesicles.Methods in molecular biology (Clifton, N.J.) · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Catarina I G D CastanheiraInstitute of Life Course and Medical Sciences, University of Liverpool, Liverpool L7 8TX, UK.
James R AndersonInstitute of Life Course and Medical Sciences, University of Liverpool, Liverpool L7 8TX, UK.ORCID 0000-0003-0489-7997
Emily J ClarkeInstitute of Life Course and Medical Sciences, University of Liverpool, Liverpool L7 8TX, UK.
Matthias HacklTAmiRNA GmbH, 1110 Vienna, Austria.
Victoria JamesSchool of Veterinary Medicine and Science, University of Nottingham, Nottingham LE12 5RD, UK.ORCID 0000-0002-9926-2953
Peter D CleggInstitute of Life Course and Medical Sciences, University of Liverpool, Liverpool L7 8TX, UK.
Mandy J PeffersInstitute of Life Course and Medical Sciences, University of Liverpool, Liverpool L7 8TX, UK.

Funding

Medical Research Council (MRC) and Versus Arthritis as part of the Medical Research Council Versus Arthritis Centre for Integrated Research into Musculoskeletal Ageing MR/P020941/1The Horse Trust G5018Wellcome TrustWellcome Trust Clinical Intermediate Fellowship 107471/Z/15/Z
6 · The paper itself

Abstract

This study describes a novel technique to analyze the extracellular vesicle (EV)-derived microRNA (miRNA) crosstalk between equine chondrocytes and synoviocytes. Donor cells (chondrocytes,

Indexed as

ChondrocytesExtracellular VesiclesMicroRNAsSynoviocytesAnimalsCell CommunicationCells, CulturedGene Expression RegulationHorsesMicroRNAs5-ethynyl uridineequineextracellular vesiclemicroRNAosteoarthritissmall RNA sequencingsynovial fluid

Identifiers

PMID40244190
PMCPMC11989968

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.