Evidence map›Paper›PMID 40244142›Full record

ArticleInternational journal of molecular sciences2025

Mn

Yuriy Kot, Volodymyr Prokopiuk, Vladimir Klochkov, Liliya Tryfonyuk, Pavel Maksimchuk, Andrey Aslanov, Kateryna Kot, Oleg Avrunin, Lesya Demchenko, Saulesh Kurmangaliyeva and 4 more

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Tasisulam-induced suicidal death of human erythrocytes.Biochemistry and biophysics reports · 2026
    Article
  2. Article
  3. Review
  4. Article
  5. Review
  6. Cepharanthine Promotes CaInternational journal of molecular sciences · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Yuriy KotDepartment of Biochemistry, V.N. Karazin Kharkiv National, 4 Svobody sq, 61022 Kharkiv, Ukraine.
Volodymyr ProkopiukDepartment of Cryobiochemistry, Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, 23 Pereyaslavskaya st, 61015 Kharkiv, Ukraine.ORCID 0000-0003-4379-4130
Vladimir KlochkovDepartment of Nanostructured Materials, Institute for Scintillation Materials of the National Academy of Sciences of Ukraine, 60 Nauky ave, 61072 Kharkiv, Ukraine.
Liliya TryfonyukInstitute of Health, National University of Water and Environmental Engineering, 11 Soborna st, 33028 Rivne, Ukraine.ORCID 0000-0003-0307-3048
Pavel MaksimchukDepartment of Nanostructured Materials, Institute for Scintillation Materials of the National Academy of Sciences of Ukraine, 60 Nauky ave, 61072 Kharkiv, Ukraine.
Andrey AslanovDepartment of Nanostructured Materials, Institute for Scintillation Materials of the National Academy of Sciences of Ukraine, 60 Nauky ave, 61072 Kharkiv, Ukraine.
Kateryna KotDepartment of Biochemistry, V.N. Karazin Kharkiv National, 4 Svobody sq, 61022 Kharkiv, Ukraine.
Oleg AvruninDepartment of Biomedical Engineering, Kharkiv National University of Radio Electronics, 14 Nauky ave, 61116 Kharkiv, Ukraine.
Lesya DemchenkoDepartment of Chemistry, Stockholm University, Svante Arrhenius väg 16C, SE-106 91 Stockholm, Sweden.ORCID 0000-0002-2325-1940
Saulesh KurmangaliyevaDepartment of Microbiology, Virology and Immunology, West Kazakhstan Marat Ospanov Medical University, 68 Maresyev st, Aktobe 030012, Kazakhstan.
Anatolii OnishchenkoDepartment of Cryobiochemistry, Institute for Problems of Cryobiology and Cryomedicine of the National Academy of Sciences of Ukraine, 23 Pereyaslavskaya st, 61015 Kharkiv, Ukraine.
Svetlana YefimovaDepartment of Nanostructured Materials, Institute for Scintillation Materials of the National Academy of Sciences of Ukraine, 60 Nauky ave, 61072 Kharkiv, Ukraine.
Ondrej HavranekBIOCEV, First Faculty of Medicine, Charles University, Průmyslová 595, 25250 Vestec, Czech Republic.ORCID 0000-0001-5826-3557
Anton TkachenkoBIOCEV, First Faculty of Medicine, Charles University, Průmyslová 595, 25250 Vestec, Czech Republic.ORCID 0000-0002-1029-1636

Funding

European Hematology Association EHA Ukraine Bridge FundingMEYS CR CooperatioMH CR DRO - VFN00064165NICR EXCELES - LX22NPO5102
6 · The paper itself

Abstract

Accumulating evidence suggests that manganese oxide nanoparticles (NPs) show multiple enzyme-mimicking antioxidant activities, which supports their potential in redox-targeting therapeutic strategies for diseases with impaired redox signaling. However, the systemic administration of any NP requires thorough hemocompatibility testing. In this study, we assessed the hemocompatibility of synthesized Mn

Indexed as

CalciumCalpainCaspasesCell MembraneEryptosisManganese CompoundsNanoparticlesOxidesReactive Nitrogen SpeciesReactive Oxygen SpeciesErythrocytesHemolysisHumansCalciumCalpainCaspasesManganese Compoundsmanganese oxideOxidesReactive Nitrogen SpeciesReactive Oxygen Speciescalcium signalingcytotoxicityeryptosisnanoparticlesoxidative stressregulated cell death

Identifiers

PMID40244142
PMCPMC11989249

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.