Evidence map›Paper›PMID 40244106›Full record

ArticleInternational journal of molecular sciences2025

Antibacterial Properties of Polymeric Membranes Containing Doxycycline for Potential Applications in Foot Ulcer Treatment.

Stevaly Pérez-Gutiérrez, Jesús Ángel Ramírez-Enciso, Laura Abisai Pazos-Rojas, Abigailt Flores-Ledesma, Eric Reyes-Cervantes, Diana Del C Pazos-Guarneros, Ismael Juárez-Díaz, Paola G Gordillo-Guerra, Bernardino Isaac Cerda-Cristerna, José Luis Suárez-Franco and 5 more

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Stevaly Pérez-GutiérrezFaculty of Medicine, Meritorious Autonomous University of Puebla (BUAP), Puebla 72410, Mexico.
Jesús Ángel Ramírez-EncisoFaculty of Medicine, Meritorious Autonomous University of Puebla (BUAP), Puebla 72410, Mexico.
Laura Abisai Pazos-RojasFaculty of Stomatology, Meritorious Autonomous University of Puebla (BUAP), Puebla 72410, Mexico.ORCID 0000-0002-0945-4012
Abigailt Flores-LedesmaFaculty of Stomatology, Meritorious Autonomous University of Puebla (BUAP), Puebla 72410, Mexico.ORCID 0000-0002-8136-4820
Eric Reyes-CervantesDireccion de Innovación y Transferencia de Conocimiento, Meritorious Autonomous University of Puebla, Puebla 72592, Mexico.
Diana Del C Pazos-GuarnerosFaculty of Stomatology, Meritorious Autonomous University of Puebla (BUAP), Puebla 72410, Mexico.
Ismael Juárez-DíazFaculty of Stomatology, Meritorious Autonomous University of Puebla (BUAP), Puebla 72410, Mexico.
Paola G Gordillo-GuerraDepartamento de Sistemas Biológicos, Unidad Xochimilco, Universidad Autónoma Metropolitana, Coyoacan, Calzada del Hueso 1100, Col. Villa-Quietud, Ciudad de México 09310, Mexico.ORCID 0000-0002-4600-5574
Bernardino Isaac Cerda-CristernaFacultad de Odontología, Universidad Veracruzana, Región Orizaba-Córdoba, Orizaba 94732, Mexico.
José Luis Suárez-FrancoFacultad de Odontología, Universidad Veracruzana, Región Orizaba-Córdoba, Orizaba 94732, Mexico.ORCID 0000-0003-0234-0570
Carolina Samano-ValenciaFaculty of Stomatology, Meritorious Autonomous University of Puebla (BUAP), Puebla 72410, Mexico.ORCID 0000-0002-3357-4372
Brenda Erendida Castillo-SilvaFaculty of Stomatology, Meritorious Autonomous University of Puebla (BUAP), Puebla 72410, Mexico.ORCID 0000-0003-0142-895X
Alejandro G Martínez-GuerreroFaculty of Stomatology, Meritorious Autonomous University of Puebla (BUAP), Puebla 72410, Mexico.
Gisela N Rubin de Celis-QuintanaFaculty of Stomatology, Meritorious Autonomous University of Puebla (BUAP), Puebla 72410, Mexico.
Alberto V Jerezano-DomínguezFaculty of Stomatology, Meritorious Autonomous University of Puebla (BUAP), Puebla 72410, Mexico.ORCID 0000-0003-2970-6499

Funding

Faculty of Stomatology, Meritorious Autonomous University of Puebla (BUAP) 142/2025
6 · The paper itself

Abstract

Membranes made from biopolymers and loaded with doxycycline were investigated for potential use in the treatment of foot ulcers in diabetic patients. Carboxymethylcellulose (CMC) and chitosan (CHS) membranes were fabricated with 7% glycerol and 1% doxycycline (DOX). Their mechanical and physical properties, biocompatibility, and antimicrobial effects were thoroughly evaluated. The results demonstrated effective antibacterial activity against

Indexed as

Anti-Bacterial AgentsDoxycyclineFoot UlcerMembranes, ArtificialCarboxymethylcellulose SodiumChitosanHumansMicrobial Sensitivity TestsStaphylococcus aureusStreptococcus mutansAnti-Bacterial AgentsCarboxymethylcellulose SodiumChitosanDoxycyclineMembranes, Artificialcarboxymethylcellulosechitosanfoot ulcers Escherichia colimembraneStaphylococcus aureusStreptococcus mutans

Identifiers

PMID40244106
PMCPMC11989348

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.