Evidence map›Paper›PMID 40244097›Full record

ArticleInternational journal of molecular sciences2025

The Influence of AQP5 on the Response to Hydrogen Peroxide in Breast Cancer Cell Lines.

Ivan Lučić, Monika Mlinarić, Ana Čipak Gašparović, Lidija Milković

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Gut microbes · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ivan LučićLaboratory for Membrane Transport and Signaling, Division of Molecular Medicine, Ruđer Bošković Institute, Bijenička Cesta 54, 10000 Zagreb, Croatia.ORCID 0000-0002-1017-7569
Monika MlinarićLaboratory for Membrane Transport and Signaling, Division of Molecular Medicine, Ruđer Bošković Institute, Bijenička Cesta 54, 10000 Zagreb, Croatia.ORCID 0000-0003-2222-7559
Ana Čipak GašparovićLaboratory for Membrane Transport and Signaling, Division of Molecular Medicine, Ruđer Bošković Institute, Bijenička Cesta 54, 10000 Zagreb, Croatia.ORCID 0000-0003-2000-8950
Lidija MilkovićLaboratory for Membrane Transport and Signaling, Division of Molecular Medicine, Ruđer Bošković Institute, Bijenička Cesta 54, 10000 Zagreb, Croatia.ORCID 0000-0002-4484-039X

Funding

Croatian Science Foundation IP-2020-02-3617
6 · The paper itself

Abstract

Breast cancer is a heterogeneous disease with varying responses to therapies. While targeted treatments have advanced, conventional therapies inducing oxidative stress remain widely used. H

Indexed as

Aquaporin 5Breast NeoplasmsHydrogen PeroxideAquaporin 3Cell Line, TumorCell SurvivalFemaleGene Expression Regulation, NeoplasticHumansMCF-7 CellsNF-E2-Related Factor 2Oxidative StressPhosphatidylinositol 3-KinasesProto-Oncogene Proteins c-aktReactive Oxygen SpeciesSignal TransductionAQP5 protein, humanAquaporin 3Aquaporin 5Hydrogen PeroxideNF-E2-Related Factor 2Phosphatidylinositol 3-KinasesProto-Oncogene Proteins c-aktReactive Oxygen SpeciesAQP3AQP5cell viabilityFOXOshydrogen peroxideNRF2 signalingPI3K/AKT signalingROS production

Identifiers

PMID40244097
PMCPMC11989815

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.