Evidence map›Paper›PMID 40243890›Full record

ReviewInternational journal of molecular sciences2025

The Significance of Fungal Specialized Metabolites in One Health Perspectives.

Pierluigi Reveglia, Carmela Paolillo, Gaetano Corso

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Pierluigi RevegliaDepartment of Clinical and Experimental Medicine, University of Foggia, 71122 Foggia, Italy.ORCID 0000-0003-0588-2092
Carmela PaolilloDepartment of Clinical and Experimental Medicine, University of Foggia, 71122 Foggia, Italy.ORCID 0000-0003-2677-5747
Gaetano CorsoDepartment of Clinical and Experimental Medicine, University of Foggia, 71122 Foggia, Italy.ORCID 0000-0003-4720-1320

Funding

Ministero dell'Università e della Ricerca 20222ZB4HK
6 · The paper itself

Abstract

Among the emerging threats in global health, fungal pathogens stand out as some of the most important, causing over 1.6 million deaths annually and destroying a third of all food crops each year, exacerbating food insecurity and economic losses. Climate change further amplifies the threat by enabling pathogenic fungi to survive at mammalian temperatures, increasing risks of zoonotic transmission and antifungal resistance. In this context, interdisciplinary research, particularly the One Health approach, is crucial for understanding the evolution of fungal resistance and improving diagnostic and therapeutic tools. Drawing lessons from agriculture, where integrated pest management strategies successfully mitigate fungal threats, could offer new ways to tackle fungal infections in humans. Advanced metabolomics and diagnostics, including fungal metabolites as biomarkers, hold promise for early detection and personalized treatment. Collaborative efforts between medicine, veterinary science, and plant pathology are essential to develop new antifungal drugs and improve clinical management of fungal diseases, fostering a more resilient global health system.

Indexed as

FungiMycosesOne HealthAnimalsAntifungal AgentsDrug Resistance, FungalHumansMetabolomicsAntifungal Agentsfungal metabolitesmetabolomicsOne Health

Identifiers

PMID40243890
PMCPMC11988512

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.