Evidence map›Paper›PMID 40243798›Full record

ArticleRevista do Instituto de Medicina Tropical de Sao Paulo2025

Leptospirosis and coinfections leading to fatal multiple organ and system failure.

Luiza Schettini Marotto, Marcia Schettini Marotto, Tomás Zecchini Barrese, Cinthya Dos Santos Cirqueira Borges, Juliana Mariotti Guerra, Leonardo José Tadeu de Araújo, Camila Santos da Silva Ferreira, Amir Nassar Filho, Paulo Cesar Fumagalli Marotto

Abstract readCase Reports
In one paragraph

Article in Revista do Instituto de Medicina Tropical de Sao Paulo, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Luiza Schettini MarottoHospital Municipal Antonio Giglio, Osasco, São Paulo, Brazil.ORCID http://orcid.org/0000-0002-9480-9286
Marcia Schettini MarottoHospital Municipal Antonio Giglio, Osasco, São Paulo, Brazil.
Tomás Zecchini BarreseInstituto Adolfo Lutz, Departamento de Patologia, São Paulo, São Paulo, Brazil.ORCID http://orcid.org/0000-0002-7770-5303
Cinthya Dos Santos Cirqueira BorgesInstituto Adolfo Lutz, Departamento de Patologia, São Paulo, São Paulo, Brazil.ORCID http://orcid.org/0000-0002-3719-5505
Juliana Mariotti GuerraInstituto Adolfo Lutz, Departamento de Patologia, São Paulo, São Paulo, Brazil.ORCID http://orcid.org/0000-0002-0326-7187
Leonardo José Tadeu de AraújoInstituto Adolfo Lutz, Departamento de Patologia, São Paulo, São Paulo, Brazil.ORCID http://orcid.org/0000-0002-5427-4053
Camila Santos da Silva FerreiraInstituto Adolfo Lutz, Departamento de Patologia, São Paulo, São Paulo, Brazil.ORCID http://orcid.org/0000-0002-0386-5486
Amir Nassar FilhoHospital Municipal Antonio Giglio, Osasco, São Paulo, Brazil.
Paulo Cesar Fumagalli MarottoUniversidade Nove de Julho (Campus Vergueiro), Faculdade de Medicina, São Paulo, São Paulo, Brazil.ORCID http://orcid.org/0009-0008-7898-6515

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Coinfection with leptospirosis and other infectious agents pose major challenges in medical practice, often due to difficulties in isolating these agents, symptoms overlap, and lack of specific investigation protocols in areas with emerging and re-emerging diseases. Consequently, knowledge regarding these coinfections and their impact on clinical outcomes are limited. A previously healthy 33-year-old woman, with no history of chronic or malignance diseases, was admitted with febrile icteric illness, pulmonary hemorrhage, acute kidney injury, thrombocytopenia, and shock. Leptospirosis, COVID-19, human rhinovirus, and dengue in the acute phase were clinically and pathologically diagnosed. Multiple coinfections can rapidly lead to multiple organ and system failure, often resulting in a fatal outcome.

Indexed as

CoinfectionCOVID-19DengueLeptospirosisMultiple Organ FailureAdultFatal OutcomeFemaleHumans

Identifiers

PMID40243798
PMCPMC11996032

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.