Evidence map›Paper›PMID 40243704›Full record

ArticleInternational journal of molecular sciences2025

Urolithin A Protects Porcine Oocytes from Artificially Induced Oxidative Stress Damage to Enhance Oocyte Maturation and Subsequent Embryo Development.

Wen Shi, Chaobin Qin, Yanyan Yang, Xiaofen Yang, Yizhen Fang, Bing Zhang, Dong Wang, Wanyou Feng, Deshun Shi

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Wen ShiGuangxi Key Laboratory of Animal Breeding & Disease Control and Prevention, College of Animal Science and Technology, Guangxi University, Nanning 530004, China.
Chaobin QinGuangxi Key Laboratory of Animal Breeding & Disease Control and Prevention, College of Animal Science and Technology, Guangxi University, Nanning 530004, China.
Yanyan YangGuangxi Key Laboratory of Animal Breeding & Disease Control and Prevention, College of Animal Science and Technology, Guangxi University, Nanning 530004, China.
Xiaofen YangGuangxi Key Laboratory of Animal Breeding & Disease Control and Prevention, College of Animal Science and Technology, Guangxi University, Nanning 530004, China.
Yizhen FangGuangxi Key Laboratory of Animal Breeding & Disease Control and Prevention, College of Animal Science and Technology, Guangxi University, Nanning 530004, China.
Bing ZhangGuangxi Key Laboratory of Animal Breeding & Disease Control and Prevention, College of Animal Science and Technology, Guangxi University, Nanning 530004, China.
Dong WangGuangxi Key Laboratory of Animal Breeding & Disease Control and Prevention, College of Animal Science and Technology, Guangxi University, Nanning 530004, China.
Wanyou FengSchool of Environmental and Life Sciences, Nanning Normal University, Nanning 530001, China.
Deshun ShiGuangxi Key Laboratory of Animal Breeding & Disease Control and Prevention, College of Animal Science and Technology, Guangxi University, Nanning 530004, China.ORCID 0000-0002-8735-5925

Funding

National Natural Science Foundation of China 31972996
6 · The paper itself

Abstract

Both the livestock and biomedical fields require a large supply of high-quality mature oocytes. However, the in vitro maturation (IVM) process often leads to an accumulation of reactive oxygen species (ROS), which can cause defects in oocyte meiosis and embryo development, ultimately compromising oocyte quality. Urolithin A (UA), known for its antioxidant properties, has not been thoroughly investigated for its potential to mitigate the negative effects of oxidative stress during the in vitro culturing of oocytes, and its underlying mechanism is not well understood. In this study, an in vitro oxidative stress model was established using porcine oocytes treated with H

Indexed as

CoumarinsEmbryonic DevelopmentOocytesOxidative StressAnimalsAntioxidantsApoptosisDNA DamageFemaleHydrogen PeroxideIn Vitro Oocyte Maturation TechniquesMitochondriaReactive Oxygen SpeciesSwine3,8-dihydroxy-6H-dibenzo(b,d)pyran-6-oneAntioxidantsCoumarinsHydrogen PeroxideReactive Oxygen Speciesautophagyembryo developmentmeiotic maturationmitochondrial functionoocyte qualityoxidative stressurolithin A

Identifiers

PMID40243704
PMCPMC11989139

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.