Evidence map›Paper›PMID 40243660›Full record

ArticleInternational journal of molecular sciences2025

Differential Cellular Responses to Class I and II Sphingomyelinase D: Unraveling the Mechanisms of

Bruna Fernandes Pinto, Priscila Hess Lopes, Carlos Eduardo Madureira Trufen, Ana Tung Ching Ching, Inácio de Loyola M Junqueira de Azevedo, Milton Yutaka Nishiyama-Jr, Marcelo Medina de Souza, Paula C Pohl, Denise V Tambourgi

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Bruna Fernandes PintoImmunochemistry Laboratory, Butantan Institute, Avenue Vital Brasil, 1500, Butantã, São Paulo 05503-900, Brazil.
Priscila Hess LopesImmunochemistry Laboratory, Butantan Institute, Avenue Vital Brasil, 1500, Butantã, São Paulo 05503-900, Brazil.ORCID 0000-0001-6670-2564
Carlos Eduardo Madureira TrufenPREVOR, Rue des Chasseurs-Ardennais 3, 4031 Liège, Belgium.ORCID 0000-0003-1216-0418
Ana Tung Ching ChingImmunochemistry Laboratory, Butantan Institute, Avenue Vital Brasil, 1500, Butantã, São Paulo 05503-900, Brazil.ORCID 0009-0004-2626-7894
Inácio de Loyola M Junqueira de AzevedoLaboratoy of Applied Toxinology, Butantan Institute, Avenue Vital Brasil, 1500, Butantã, São Paulo 05503-900, Brazil.
Milton Yutaka Nishiyama-JrLaboratoy of Applied Toxinology, Butantan Institute, Avenue Vital Brasil, 1500, Butantã, São Paulo 05503-900, Brazil.ORCID 0000-0002-2410-0562
Marcelo Medina de SouzaCentre of Excellence in New Target Discovery, Butantan Institute, Avenue Vital Brasil, 1500, Butantã, São Paulo 05503-900, Brazil.
Paula C PohlImmunochemistry Laboratory, Butantan Institute, Avenue Vital Brasil, 1500, Butantã, São Paulo 05503-900, Brazil.ORCID 0000-0001-8569-8150
Denise V TambourgiImmunochemistry Laboratory, Butantan Institute, Avenue Vital Brasil, 1500, Butantã, São Paulo 05503-900, Brazil.ORCID 0000-0003-1896-9074

Funding

São Paulo Research Foundation 2013/07467-1
6 · The paper itself

Abstract

Dermonecrosis resulting from

Indexed as

Phosphoric Diester HydrolasesSpider VenomsAnimalsApoptosisHumansKeratinocytesNecrosisSignal TransductionSubstance PVascular Endothelial Growth Factor Aloxosceles venomPhosphoric Diester Hydrolasessphingomyelin phosphodiesterase DSpider VenomsSubstance PVascular Endothelial Growth Factor Adermonecrotic lesionLoxosceles venomsphingomyelinase Dsubstance PVEGF-Awound healing

Identifiers

PMID40243660
PMCPMC11988295

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.