SynthesisInternational journal of molecular sciences2025
Investigating the Role of Skin Autofluorescence in Gestational Diabetes Mellitus: A Systematic Review.
Synthesis in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Could Skin Autofluorescence Be a Useful Biomarker in Systemic Lupus Erythematosus? A Systematic Review.International journal of molecular sciences · 2025Pooled it
- Exploring Continuous Glucose Monitoring in Gestational Diabetes: A Systematic Review.Life (Basel, Switzerland) · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Gestational diabetes mellitus (GDM) is a pregnancy-specific condition that can cause serious complications for both the mother and the fetus. Preventing these complications requires optimum glycemic control. Skin autofluorescence (SAF) is a non-invasive and innovative method that evaluates the levels of advanced glycation end products, markers of hyperglycemia, that could aid in the optimum management of GDM-complicated pregnancies. This systematic review aims to assess SAF's potential utility in the prediction of short-term and long-term outcomes in GDM. Following the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) methodology, with the protocol identifier CRD42024559012, we used "(skin autofluorescence OR SAF) AND (gestational diabetes mellitus OR GDM)" as a search criterion on the PubMed, Scopus, and Web of Science databases. After a rigorous selection process, we included five articles, which evaluated SAF values and GDM, SAF and pregnancies complicated by diabetes mellitus, and SAF and macrosomia. GDM diagnosis varies due to the different approaches among the major guidelines, leading to variations in interpretation and diagnostic thresholds. Across studies, this variability contributes to inconsistent SAF values. As a standardized and objective marker, SAF could provide a uniform criterion, improving GDM management. Further research is needed to validate its clinical utility.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.