Evidence map›Paper›PMID 40243431›Full record

ArticleInternational journal of molecular sciences2025

Placental Molecular Expression of Different Pathogenic Vaginal Infections.

Daniela Roxana Matasariu, Constantin Condac, Victoria Bîrluțiu, Ludmila Lozneanu, Iuliana Elena Bujor, Vasile Lucian Boiculese, Mihai Sava, Alexandra Ursache

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Daniela Roxana MatasariuDepartment of Obstetrics and Gynecology, "Cuza Voda" Hospital, 700038 Iasi, Romania.ORCID 0000-0002-2862-2069
Constantin CondacDepartment of Anesthesia and Intensive Care, "Cuza Voda" Hospital, 700038 Iasi, Romania.
Victoria BîrluțiuDepartment of Infectious Diseases, University of Medicine and Pharmacy "Lucian Blaga", 550169 Sibiu, Romania.ORCID 0000-0001-7391-3394
Ludmila LozneanuDepartment of Morpho-Functional Sciences I-Histology, University of Medicine and Pharmacy "Gr. T. Popa", 700115 Iasi, Romania.ORCID 0000-0002-3994-6579
Iuliana Elena BujorDepartment of Mother and Child, University of Medicine and Pharmacy "Gr. T. Popa", 700115 Iasi, Romania.
Vasile Lucian BoiculeseBiostatistics, Department of Preventive Medicine and Interdisciplinarity, University of Medicine and Pharmacy "Gr. T. Popa", 700115 Iasi, Romania.ORCID 0000-0001-5825-6189
Mihai SavaDepartment of Anesthesia and Intensive Care, University of Medicine and Pharmacy "Lucian Blaga", 550169 Sibiu, Romania.ORCID 0000-0002-4482-2618
Alexandra UrsacheDepartment of Mother and Child, University of Medicine and Pharmacy "Gr. T. Popa", 700115 Iasi, Romania.ORCID 0000-0002-8207-7655

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study evaluated the differential expression of four placental markers-vitamin D receptor (VDR), Cluster of Differentiation 44 (CD44), osteopontin (OPN), and cyclooxygenase-2 (COX-2)-in response to pathogens, which may contribute to our understanding of pathogen-specific impacts on pregnancy outcomes. We immunohistochemically (IHC) analyzed placental tissues obtained from 70 healthy-term pregnant women in the control group and compared them to tissues obtained from 78 women with pregnancy above 24 weeks of gestation, single-pathogen vaginal infection, and premature rupture of membranes/preterm premature rupture of membranes (PROM/PPROM). We detected high expression of these four molecules in cases of

Indexed as

PlacentaPregnancy Complications, InfectiousVaginosis, BacterialAdultBiomarkersCyclooxygenase 2FemaleHumansHyaluronan ReceptorsOsteopontinPregnancyReceptors, CalcitriolStreptococcus agalactiaeBiomarkersCD44 protein, humanCyclooxygenase 2Hyaluronan ReceptorsOsteopontinReceptors, CalcitriolVDR protein, humanCandidaCD44chorioamnionitisCOX-2Group B StreptococcusKlebsiellaosteopontinplacentaUreaplasma urealyticumvitamin D receptor

Identifiers

PMID40243431
PMCPMC11988318

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.