Evidence map›Paper›PMID 40243340›Full record

ArticleXenotransplantation

Religious Perspectives Regarding the Ethical Issues Associated With Clinical Xenotransplantation.

Daniel J Hurst, Mansur Ali, Samuel M Brown, Joris Gielen, Komal Kashyap, Terri Laws, John Loike, Renzo Pegoraro, Jonah Rubin, Martha Stebbins and 4 more

Abstract read
In one paragraph

Article in Xenotransplantation. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Daniel J HurstDepartment of Medical Education and Scholarship, Rowan-Virtua School of Osteopathic Medicine, Stratford, New Jersey, USA.ORCID 0000-0003-0592-2592
Mansur AliCentre for the Study of Islam in the UK, School of History, Archaeology and Religion, Cardiff University, Cardiff, UK.ORCID 0000-0002-3176-4746
Samuel M BrownDepartment of Internal Medicine, University of Utah School of Medicine, Salt Lake City, Utah, USA.ORCID 0000-0003-1206-6261
Joris GielenCenter for Global Health Ethics, Duquesne University, Pittsburgh, Pennsylvania, USA.ORCID 0000-0002-8433-6745
Komal KashyapDepartment of Onco-Anaesthesia & Palliative Medicine, All India Institute of Medical Sciences, Chhattisgarh, India.ORCID 0000-0001-6541-6793
Terri LawsAfrican American Studies Program, University of Michigan, Dearborn, Michigan, USA.ORCID 0000-0002-5934-0646
John LoikeCo-Director of Biomedical Ethics and Humanities, New York Medical College, New York City, New York, USA.
Renzo PegoraroPontifical Academy for Life, Vatican City.ORCID 0000-0002-9368-7950
Jonah RubinDepartment of Pulmonary and Critical Care Medicine, Corrigan Minehan Heart Center ICU, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.ORCID 0000-0002-3252-2095
Martha StebbinsBishop of Montana, The Episcopal Church in the USA, Helena, Montana, USA.ORCID 0009-0007-0978-4795
Andrew T WalkerSchool of Theology, The Southern Baptist Theological Seminary, Louisville, Kentucky, USA.
Syed Shabih Haider ZaidiUK National Health Service, London, UK.
Richard N PiersonCenter for Transplantation Sciences and, Division of Cardiac Surgery, Department of Surgery, Massachusetts General Hospital, Boston, Massachusetts, USA.ORCID 0000-0003-3764-4590
Emanuele CozziTransplant Immunology Unit, Department of Cardiac, Thoracic, and Vascular Sciences, Padua University Hospital, Veneto, Italy.ORCID 0000-0001-7855-5055

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAs xenotransplantation advances toward clinical trials, viewpoints from various segments of society are continually needed to engage the public and to inform the prospective clinical trials. As the majority of the world's population identifies with a religious tradition, religious perspectives regarding the ethical issues associated with clinical xenotransplantation are an important element to take into account.

methodsAt the 2024 Congress of The Transplantation Society in Istanbul, Türkiye, a group of religious scholars from Catholicism, The Church of Jesus Christ of Latter-day Saints, Hinduism, Shia Islam, Judaism, Protestant Christianity, and the African American religious traditions met together to discuss viewpoints toward xenotransplantation from their respective religious tradition. Additional contributions were received from representatives from the American Anglican Episcopal Church and Sunni Islam faith traditions.

resultsEach speaker presented viewpoints on the ethical issues associated with clinical xenotransplantation from their own religious perspective. Common issues that were raised include the treatment and stewardship of animals, xenozoonotic infection and other risks, while religious dictums of particular relevance for each faith tradition were noted.

conclusionOverall, none of the participants considered xenotransplantation to be impermissible within their religious tradition. Yet, it is important to note that persons of religious faith may come to different conclusions from their coreligionists about the permissibility of xenotransplantation as a personal choice or as spokespersons for others of their faith. Additional empirical viewpoint data from each religious tradition will be helpful to further inform normative views and measure the impact of public education. As xenotransplantation continues to advance to the clinic, continued exploration of religious perspectives is needed to best support individual decision-making and optimize patient-centered care.

Indexed as

HeterograftsReligionReligion and MedicineTransplantation, HeterologousAnimalsHumansethicsorgan transplantationreligionxenotransplantation

Identifiers

PMID40243340
PMCPMC12005069

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.