Evidence map›Paper›PMID 40243195›Full record

ArticleCancer medicine2025

Global incidence, risk factors, and temporal trends of nasal cancer: A population-based analysis.

Junjie Huang, Wing Sze Pang, Fung Yu Mak, Sze Chai Chan, Veeleah Lok, Lin Zhang, Xu Lin, Don Eliseo Lucero-Prisno, Wanghong Xu, Zhi-Jie Zheng and 4 more

Abstract read
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In one paragraph

Article in Cancer medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Junjie HuangThe Jockey Club School of Public Health and Primary Care, Faculty of Medicine, Chinese University of Hong Kong, Hong Kong, SAR, China.ORCID https://orcid.org/0000-0003-2382-4443
Wing Sze PangThe Jockey Club School of Public Health and Primary Care, Faculty of Medicine, Chinese University of Hong Kong, Hong Kong, SAR, China.
Fung Yu MakThe Jockey Club School of Public Health and Primary Care, Faculty of Medicine, Chinese University of Hong Kong, Hong Kong, SAR, China.
Sze Chai ChanThe Jockey Club School of Public Health and Primary Care, Faculty of Medicine, Chinese University of Hong Kong, Hong Kong, SAR, China.
Veeleah LokDepartment of Global Public Health, Karolinska Institute, Karolinska University Hospital, Stockholm, Sweden.
Lin ZhangSuzhou Industrial Park Monash Research Institute of Science and Technology, Suzhou, China.
Xu LinDepartment of Thoracic Surgery, The First Affiliated Hospital, School of Medicine, Zhejiang University, Zhejiang, Hangzhou, China.
Don Eliseo Lucero-PrisnoDepartment of Global Health and Development, London School of Hygiene and Tropical Medicine, London, UK.
Wanghong XuSchool of Public Health, Fudan University, Shanghai, China.ORCID https://orcid.org/0000-0003-2045-2218
Zhi-Jie ZhengDepartment of Global Health, School of Public Health, Peking University, Beijing, China.
Edmar ElcarteUniversity of the Philippines, Manila, Philippines.
Mellissa WithersDepartment of Population and Health Sciences, Institute for Global Health, University of Southern California, Los Angeles, California, USA.
Martin C S WongThe Jockey Club School of Public Health and Primary Care, Faculty of Medicine, Chinese University of Hong Kong, Hong Kong, SAR, China.
NCD Global Health Research Group, Association of Pacific Rim Universities (APRU)

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundNasal cancer is a rare and fatal disease, with an incidence rate of <1 in 100,000, and a 5-year survival rate of around 30%. The study aims to investigate the worldwide disease burden, associated risk factors, and temporal incidence patterns of nasal cancer.

methodsData were obtained from multiple sources, including the Global Cancer Observatory, Cancer Incidence in Five Continents Plus, the Global Burden of Disease database, the World Bank, and the United Nations. The study utilized multivariable linear regression to investigate the relationship between risk factors and the incidence of nasal cancer by age for each country. Trend analysis was conducted using the joinpoint regression analysis program, and the average annual percentage change (AAPC) was calculated. The accuracy of trend estimations was assessed using the 95% confidence interval (CI). Additionally, the incidence of nasal cancer was examined by age and geographic location.

resultsA total of 37,674 new cases were reported in 2020 (ASR 4.2 per 1,000,000). The highest ASRs were observed in South-Eastern Asia (5.3) and Central and Eastern Europe (4.8). A number of risk factors were identified, such as higher HDI regions, higher prevalence of smoking, alcohol drinking, unhealthy dietary, and hypertension. In addition, physical inactivity was related to lower incidence. An overall decreasing trend was reported in the global population, but an increasing trend was discovered in males.

conclusionsThe highest burden of nasal cancer was found in South-Eastern Asia and Central and Eastern Europe, potentially due to regional genetic factors and pollution issues. Targeted interventions are need in high-risk regions. Further studies are needed to investigate factors contributing to the increasing temporal trend of nasal cancer among the male population.

Indexed as

Nose NeoplasmsAdolescentAdultAgedAged, 80 and overFemaleGlobal Burden of DiseaseGlobal HealthHumansIncidenceMaleMiddle AgedRisk FactorsYoung Adultincidencenasal cancerrisk factorstemporal trend

Identifiers

PMID40243195
PMCPMC12004393

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.