Evidence map›Paper›PMID 40243171›Full record

ArticleCancer medicine2025

Overcome the Fear of Exercise in Patients With Bone Metastases: A Qualitative Study on Patients' Perception.

Anita Borsati, Daniela Tregnago, Matteo Caleffi, Christian Ciurnelli, Linda Toniolo, Ilaria Trestini, Lorenzo Belluomini, Marco Sposito, Jessica Insolda, Federico Schena and 3 more

Abstract read
In one paragraph

Article in Cancer medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Anita BorsatiBiomedical, Clinical and Experimental Sciences, Department of Medicine, University of Verona, Verona, Italy.
Daniela TregnagoSection of Innovation Biomedicine - Oncology Area, Department of Engineering for Innovation Medicine (DIMI), University of Verona and University and Hospital Trust (AOUI) of Verona, Verona, Italy.
Matteo CaleffiDepartment of Neurosciences, Biomedicine and Movement, University of Verona, Verona, Italy.
Christian CiurnelliDepartment of Neurosciences, Biomedicine and Movement, University of Verona, Verona, Italy.
Linda TonioloDepartment of Neurosciences, Biomedicine and Movement, University of Verona, Verona, Italy.
Ilaria TrestiniDietetic Service, Medical Direction, Azienda Ospedaliera Universitaria Integrata di Verona, Verona, Italy.
Lorenzo BelluominiSection of Innovation Biomedicine - Oncology Area, Department of Engineering for Innovation Medicine (DIMI), University of Verona and University and Hospital Trust (AOUI) of Verona, Verona, Italy.
Marco SpositoSection of Innovation Biomedicine - Oncology Area, Department of Engineering for Innovation Medicine (DIMI), University of Verona and University and Hospital Trust (AOUI) of Verona, Verona, Italy.
Jessica InsoldaSection of Innovation Biomedicine - Oncology Area, Department of Engineering for Innovation Medicine (DIMI), University of Verona and University and Hospital Trust (AOUI) of Verona, Verona, Italy.
Federico SchenaDepartment of Neurosciences, Biomedicine and Movement, University of Verona, Verona, Italy.
Michele MilellaSection of Innovation Biomedicine - Oncology Area, Department of Engineering for Innovation Medicine (DIMI), University of Verona and University and Hospital Trust (AOUI) of Verona, Verona, Italy.ORCID https://orcid.org/0000-0002-3826-5237
Sara PilottoSection of Innovation Biomedicine - Oncology Area, Department of Engineering for Innovation Medicine (DIMI), University of Verona and University and Hospital Trust (AOUI) of Verona, Verona, Italy.
Alice AvanciniDepartment of Neurosciences, Biomedicine and Movement, University of Verona, Verona, Italy.ORCID https://orcid.org/0000-0003-2439-4799

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThis qualitative study aimed to explore the experiences of patients with cancer and bone metastases who participated in a personalized exercise program.

methodsIndividual interviews were conducted through purposeful sampling of patients who attended the 3-month supervised exercise program. Using a phenomenological approach, semi-structured questions were developed to investigate the benefits, risks, facilitators, and barriers related to exercise. Data were analyzed using inductive thematic analysis.

resultsThirteen patients with mixed cancer types participated in the study. Patients recognized the physical and psychological benefits of exercise, such as improvements in physical fitness, bone health, reduction of symptoms, especially pain and fatigue, and increase in self-confidence. While they did not perceive any disadvantage from participating in the program, they acknowledged the risk of bone fractures or exacerbation of lesions if the intervention is not tailored and supervised. The program's structure, including the involvement of dedicated specialists, has been reported as a fundamental pillar. Among the modulators for participation and adherence, comorbidities associated with bone metastases, logistic barriers, and lack of social support may be obstacles. Conversely, recommendations from the oncologist, personal motivation, and peer support were found to be facilitators of practice.

conclusionsPatients with bone metastases expressed a broad range of benefits from participation in a structured exercise program. Several modulators may affect uptake and adherence and thus should be considered when designing a dedicated program.

Indexed as

Bone NeoplasmsExerciseExercise TherapyFearAdultAgedAged, 80 and overFemaleHumansMaleMiddle AgedPerceptionQualitative Researchbarriersbone metastasesexercisefacilitatorsneedsperception

Identifiers

PMID40243171
PMCPMC12004276

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.