Evidence map›Paper›PMID 40243139›Full record

ArticleJournal of magnetic resonance imaging : JMRI2025

Fetal MRI: Radiofrequency Safety Assessment at 3 Tesla.

Filiz Yetisir, Esra Abaci Turk, Henry A Feldman, Borjan Gagoski, Ryne A Didier, Carol Barnewolt, Judy A Estroff, Lawrence L Wald, Elfar Adalsteinsson, P Ellen Grant

Abstract read
In one paragraph

Article in Journal of magnetic resonance imaging : JMRI, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Filiz YetisirDepartment of Pediatrics, Harvard Medical School, Boston, Massachusetts, USA.ORCID https://orcid.org/0000-0002-3100-1159
Esra Abaci TurkDepartment of Pediatrics, Harvard Medical School, Boston, Massachusetts, USA.
Henry A FeldmanDepartment of Pediatrics, Harvard Medical School, Boston, Massachusetts, USA.
Borjan GagoskiFetal Neonatal Neuroimaging and Developmental Science Center, Boston Children's Hospital, Boston, Massachusetts, USA.ORCID https://orcid.org/0000-0003-3777-2621
Ryne A DidierDepartment of Radiology, Boston Children's Hospital, Harvard Medical School, Boston, Massachusetts, USA.
Carol BarnewoltDepartment of Radiology, Boston Children's Hospital, Harvard Medical School, Boston, Massachusetts, USA.
Judy A EstroffDepartment of Radiology, Boston Children's Hospital, Harvard Medical School, Boston, Massachusetts, USA.
Lawrence L WaldHarvard-MIT Division of Health Sciences and Technology, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA.ORCID https://orcid.org/0000-0001-8278-6307
Elfar AdalsteinssonHarvard-MIT Division of Health Sciences and Technology, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA.
P Ellen GrantDepartment of Pediatrics, Harvard Medical School, Boston, Massachusetts, USA.

Funding

Novel MRI Assessment of Placental Structure and Function Throughout PregnancyR01HD100009 · NICHD · BOSTON CHILDREN'S HOSPITAL · PI ADALSTEINSSON, ELFAR, GRANT, PATRICIA ELLEN · 2019 to 2023
$3.6M
Fetal MRI: robust self-driving brain acquisition and body movement quantificationR01EB032708 · NIBIB · BOSTON CHILDREN'S HOSPITAL · PI ADALSTEINSSON, ELFAR, GRANT, PATRICIA ELLEN · 2022 to 2025
$2.8M
Developing novel MR tools to optimize surgical planning and fetal outcome in TTTSR01HD114338 · NICHD · BOSTON CHILDREN'S HOSPITAL · PI ELFAR ADALSTEINSSON, Patricia Ellen Grant · 2024 to 2026
$2.2M
CSR NIH HHS R01EB032708CSR NIH HHS R01HD100009CSR NIH HHS R01HD114338NIBIB NIH HHS R01 EB032708NICHD NIH HHS R01 HD100009NICHD NIH HHS R01 HD114338
6 · The paper itself

Abstract

background3-T MRI can improve image quality of fetal imaging compared to 1.5-T MRI. However, concerns exist regarding increased local tissue heating at 3-T. PURPOSE: To assess fetal MRI radiofrequency (RF) safety at 3-T by comparing simulated tissue heating to 1.5-T (using constant RF exposure) and by simulating tissue heating at 3-T using RF exposures from clinical fetal examinations. STUDY TYPE: Retrospective. POPULATION: Seven voxelized anatomical pregnant body models (gestational age [GA] 30 ± 3 weeks [mean ± standard deviation], maternal body mass index [BMI] 27.8 ± 8.5 kg/m FIELD STRENGTH/SEQUENCE: 3-T, 1.5-T, HASTE, VIBE, TRUFISP, EPI, DTI. ASSESSMENT: Simulated maternal and fetal peak and average SAR, temperature, and peak thermal dose were compared at 3-T and 1.5-T for 60 min 2 W/kg wbSAR using 7 body models and a 16-rung band-pass RF coil. Temperature and thermal dose were simulated in one body model using clinical wbSAR exposures at 3-T. STATISTICAL TESTS: Factorial analysis of variance was performed using 28 maternal and fetal temperature measurements from 7 body models to detect a difference between 3-T and 1.5-T. p < 0.05 was considered statistically significant.

resultsFor constant RF exposure, we found no difference between 3-T and 1.5-T in peak maternal (1.5-T:40.38 ± 0.21°C; 3-T:40.40 ± 0.20°C; p = 0.85), peak fetal (1.5-T:39.21 ± 0.17°C; 3-T:39.09 ± 0.16°C; p = 0.19), and average maternal (1.5-T:37.32 ± 0.05°C; 3-T:37.33 ± 0.04°C; p = 0.68) temperature. We observed significantly higher average fetal temperatures at 1.5-T (1.5-T:37.75 ± 0.06°C; 3-T:37.70 ± 0.05°C). For 3-T clinical RF exposures, simulated peak temperatures exceeded the recommended limits. However, the thermal dose was below the recommended limit. DATA

conclusionFor the same RF coil geometry, local heating was similar at 3-T and 1.5-T for constant RF exposure. Although realistic 3-T RF exposures could cause peak temperatures above the recommended limits, thermal dose was below the recommended limit. EVIDENCE LEVEL: 1. TECHNICAL EFFICACY: Stage 1.

Indexed as

FetusMagnetic Resonance ImagingAdultFemaleHot TemperatureHumansMiddle AgedModels, AnatomicPregnancyPrenatal DiagnosisRadio WavesYoung Adult1.5 tesla3 teslafetal MRIRF heatingsafetySAR

Identifiers

PMID40243139
PMCPMC12335923

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.