Evidence map›Paper›PMID 40243137›Full record

ArticleAlzheimer's & dementia : the journal of the Alzheimer's Association2025

Mapping disparities in access to lecanemab in Georgia.

Niying Li, Samruddhi Nandkumar Borate, Kai Zhang, Mohammed Zuber, Yiran Han, Darshan Chudasama, Stephen Correia, Lisa Renzi-Hammond

Abstract read
In one paragraph

Article in Alzheimer's & dementia : the journal of the Alzheimer's Association, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Observational
  3. Article
  4. Article
  5. Observational
  6. Review
  7. Mapping disparities in access to lecanemab in Georgia.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025
    Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Niying LiDepartment of Clinical and Administrative Pharmacy, University of Georgia College of Pharmacy, Athens, Georgia, USA.ORCID 0000-0002-1412-9783
Samruddhi Nandkumar BorateDepartment of Clinical and Administrative Pharmacy, University of Georgia College of Pharmacy, Athens, Georgia, USA.
Kai ZhangDepartment of Population and Community Health, College of Public Health, University of North Texas Health Science Center at Fort Worth, Fort Worth, Texas, USA.
Mohammed ZuberDepartment of Clinical and Administrative Pharmacy, University of Georgia College of Pharmacy, Athens, Georgia, USA.
Yiran HanDepartment of Economics, College of Arts and Sciences, University at Albany, State University of New York, Albany, New York, USA.
Darshan ChudasamaDepartment of Epidemiology & Biostatistics, University of Georgia College of Public Health, Athens, Georgia, USA.
Stephen CorreiaInstitute of Gerontology, University of Georgia College of Public Health, Athens, Georgia, USA.
Lisa Renzi-HammondInstitute of Gerontology, University of Georgia College of Public Health, Athens, Georgia, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe approval of lecanemab-irmb offers potential disease-modifying treatments for Alzheimer's disease (AD), but geographical access barriers to infusion and amyloid positron emission tomography (PET) imaging sites might prevent timely access to the drug. We examined disparities in access to lecanemab infusion sites and amyloid PET scan facilities in Georgia's 159 counties.

methodsFacility location maps were used to examine lecanemab access. We used drive time analysis to identify and map counties by drive time.

resultsNo rural county had an amyloid PET scan center and only one had a lecanemab infusion center. Residents in rural counties need to drive > 1 hour on average to reach the nearest facility, which is statistically significantly longer than those in non-rural counties. DISCUSSION: Lack of access and long drive times pose health equity issues for those in rural counties, which already have a higher percentage of older residents and a higher prevalence of behavioral AD risk factors. HIGHLIGHTS: We mapped amyloid positron emission tomography (PET) scan and lecanemab infusion facilities in Georgia. We examined the drive time to the nearest facility in each county. One lecanemab infusion facility and no amyloid PET scan facilities were found in rural counties. The mean drive time to the nearest facility is significantly longer for rural counties. The results call for policies and resources to address this health disparity issue.

Indexed as

Alzheimer DiseaseHealthcare DisparitiesHealth Services AccessibilityGeorgiaHumansPositron-Emission TomographyRural PopulationaccessAlzheimer's diseasedisparitylecanemabrural

Identifiers

PMID40243137
PMCPMC12004269

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.