ArticleAnnals of medicine2025
CT Chest findings in IgG4-related disease.
Article in Annals of medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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1 citing paper in PubMed.
- Screening performance of sternal CT attenuation for opportunistic osteoporosis.BMC musculoskeletal disorders · 2026Article
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2 authors.
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Abstract
purposeTo investigate the multi-slice spiral Computed Tomography(MSCT) findings of chest involvement in IgG4-related diseases and to improve doctors' understanding of this disease. MATERIALS AND
methodsWe retrospectively analyzed the clinical and imaging data of 67 patients with clinically confirmed or suspected IgG4-related diseases.
resultsSixty patients (89.60%) had abnormal chest CT findings. Among them, 47 patients (70.10%) had enlarged mediastinal lymph nodes. Thickening of the tracheal and tracheobronchial perivascular walls was observed in 35 patients (52.20%). Nodules were observed in 29 patients (43.30%). Patches or ground-glass opacities were observed in 15 cases (22.40%); bilateral enlarged axillary lymph nodes, 9 (13.40%); bilateral enlarged hilar lymph nodes, 3 (4.50%); and, interstitial changes, 3 (11.90%). Pleural and pericardial effusion occurred in five cases (7.46%, two bilateral and three unilateral) and three cases (4.50%), respectively. Seven (10.45%) patients showed no obvious abnormalities. The abnormally elevated IgG4 level (>135 mg/dL) was positively correlated with thickening of the tracheal and tracheobronchial walls (
conclusionChest CT is of great significance for the diagnosis and follow-up of IgG4-RLD. Chest CT scans should be suggested to be performed when ocular symptoms, bilateral enlarged hilar lymph nodes, pancreatitis, pituitary adenitis, Takayasu arteritis, or abnormally elevated IgG4 levels (>135 mg/dL) are present, and IgG4-RLD should be considered.
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