Evidence map›Paper›PMID 40242762›Full record

ReviewFrontiers in immunology2025

Where lung cancer and tuberculosis intersect: recent advances.

Chunju Fang, Xuanlu He, Fei Tang, Zi Wang, Cong Pan, Qi Zhang, Jing Wu, Qinglan Wang, Daishun Liu, Yu Zhang

Abstract readReview
In one paragraph

Review in Frontiers in immunology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Review
  6. Article
  7. Article
  8. Review
  9. New Vistas inCancers · 2025
    Article
  10. Review
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Chunju Fang *Department of Oncology, Guizhou Provincial People's Hospital, Guiyang, China.
Xuanlu He *School of Clinical Medicine, Zunyi Medical University, Zunyi, China.
Fei Tang *Department of Oncology, Guizhou Provincial People's Hospital, Guiyang, China.
Zi WangDepartment of Oncology, Guizhou Provincial People's Hospital, Guiyang, China.
Cong PanSchool of Biological Sciences, Guizhou Education University, Guiyang, China.
Qi ZhangDepartment of Oncology, Guizhou Provincial People's Hospital, Guiyang, China.
Jing WuDepartment of Oncology, Guizhou Provincial People's Hospital, Guiyang, China.
Qinglan WangDepartment of Respiratory and Critical Care Medicine, Frontiers Science Center for Disease-related Molecular Network, West China Hospital, Sichuan University, Chengdu, China.
Daishun LiuDepartment of Respiratory and Critical Care Medicine, Guizhou Provincial People's Hospital, Guiyang, China.
Yu ZhangDepartment of Oncology, Guizhou Provincial People's Hospital, Guiyang, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lung cancer (LC) and tuberculosis (TB) represent two major global public health issues. Prior evidence has suggested a link between TB infection and an increased risk of LC. As advancements in LC treatment have led to extended survival rates for LC patients, the co-occurrence of TB and LC has grown more prevalent and poses novel clinical challenges. The intricate molecular mechanisms connecting TB and LC are closely intertwined and many issues remain to be addressed. This review focuses on resemblance between the immunosuppression in tumor and granuloma microenvironments, exploring immunometabolism, cell plasticity, inflammatory signaling pathways, microbiomics, and up-to-date information derived from spatial multi-omics between TB and LC. Furthermore, we outline immunization-related molecular mechanisms underlying these two diseases and propose future research directions. By discussing recent advances and potential targets, this review aims to establish a foundation for developing future therapeutic strategies targeting LC with concurrent TB infection.

Indexed as

Lung NeoplasmsTuberculosisTuberculosis, PulmonaryAnimalsHumansMycobacterium tuberculosisTumor Microenvironmentimmunometabolismimmunosuppressive microenvironmentsinflammationlung cancertuberculosis (TB)

Identifiers

PMID40242762
PMCPMC11999974

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.