Evidence map›Paper›PMID 40242728›Full record

ArticleAnnals of neurosciences2025

An Exploratory Randomised Trial to Assess the Effect of Nadi Shodhan Pranayama as an Adjunct Versus Standard Non-pharmacological Management in Hypertensives.

Gauri Mittal, Monika Pathania, Praag Bhardwaj, Minakshi Dhar, Meenakshi Khapre, Sunita Mittal

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Article in Annals of neurosciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Gauri MittalDepartment of Pharmacology, All India Institute of Medical Science Rishikesh, Uttarakhand, India.
Monika PathaniaDepartment of Geriatric Medicine, All India Institute of Medical Science Rishikesh, Uttarakhand, India.ORCID https://orcid.org/0000-0003-3609-1162
Praag BhardwajDepartment of Yogic Science, Faculty of Health & Wellness, Sri Sri University, Cuttack, Odisha, India.
Minakshi DharDepartment of Geriatric Medicine, All India Institute of Medical Science Rishikesh, Uttarakhand, India.
Meenakshi KhapreDepartment of Community & Family Medicine, All India Institute of Medical Science Rishikesh, Uttarakhand, India.
Sunita MittalDepartment of Physiology, All India Institute of Medical Science Rishikesh, Uttarakhand, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Nadi shodhan pranayama, which is also known as Anulom-vilom pranayama or alternate nostril breathing, has been demonstrated to elicit a decrease in systolic blood pressure (SBP), diastolic blood pressure (DBP) and heart rate, owing to its stress-reducing effects. One of the most promising quantitative markers of autonomic activity is heart rate variability (HRV). Purpose: This study was done to study the immediate and long-term effects of 10 minutes of nadi shodhan pranayama, preceded by two minutes of yogic deep abdominal breathing, on blood pressure and other autonomic parameters. Methods: Baseline parameters of BP, HRV, Pittsburgh Sleep Quality Index (PSQI) and Hamilton Anxiety Rating Scale (HAM-A) were measured at first visit. Patients were randomised into test and control groups, and the test group was given intervention. BP and HRV were measured once again immediately after intervention for test subjects. After six weeks, BP, HRV, PSQI and HAM-A were repeated. Results: Immediately after the intervention, the test group showed a significant reduction in SBP, DBP and mean heart rate (MHR) with an increase in R-R interval, standard deviation of the NN interval (SDNN), the square root of the mean squared differences of successive NN intervals and high frequency. At follow-up, the test group had a lower SBP and low frequency/high frequency ratio and a higher SDNN and total power, compared to the control group. Conclusion: The practice of nadi shodhan pranayama, preceded by two minutes of yogic deep abdominal breathing, reduced the systolic and diastolic BP and improved HRV-related autonomic parameters, in patients of hypertension on pharmacological therapy, immediately after 10 minutes of practice and after 10 minutes of daily practice for six weeks.

Indexed as

Anulom-vilom pranayamaautonomic nervous systemheart rate variabilityhypertensionnadi shodhan pranayamayoga and hypertension

Identifiers

PMID40242728
PMCPMC11996816

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.