Evidence map›Paper›PMID 40242668›Full record

ArticleJTO clinical and research reports2025

CD5 Immunoreactivity Is Associated With Longer Overall Survival in Thymic Carcinoma: A Brief Report.

Julia R Naso, Sarah M Jenkins, Julie A Vrana, Justin W Koepplin, Kenneth R Olivier, Stephen D Cassivi, Julian R Molina, Anja C Roden

Abstract read
In one paragraph

Article in JTO clinical and research reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Julia R NasoDepartment of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota.
Sarah M JenkinsDepartment of Quantitative Health Sciences, Mayo Clinic, Rochester, Minnesota.
Julie A VranaDepartment of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota.
Justin W KoepplinDepartment of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota.
Kenneth R OlivierDepartment of Radiation Oncology, Mayo Clinic, Rochester, Minnesota.
Stephen D CassiviDivision of Thoracic Surgery, Mayo Clinic, Rochester, Minnesota.
Julian R MolinaDivision of Medical Oncology, Mayo Clinic, Rochester, Minnesota.
Anja C RodenDepartment of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Thymic carcinomas are a heterogeneous group of potentially aggressive malignancies. We aimed to determine the prognostic significance of CD5, CD117, EZH2, POU2F3, BAP1, and MTAP immunohistochemical staining in thymic carcinomas. Immunohistochemistry was performed on 36 thymic carcinomas from patients with retrospectively collected survival data. Thirteen cases (36%) had CD5 staining in 50% or more tumor cells, considered positive staining. Positive CD5 immunohistochemical staining was significantly associated with longer overall survival (hazard ratio = 0.18, 95% confidence interval: 0.03-0.63,

Indexed as

CD5ImmunohistochemistryPathologyPrognosisSurvivalThymic carcinoma

Identifiers

PMID40242668
PMCPMC12000739

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.