ArticleFrontiers in chemistry2025
Highly sensitive electrochemical immunosensor based on methylene blue-reduced graphene oxide nanocomposites as signal probes for IL-6 detection in gingival crevicular fluid samples.
Article in Frontiers in chemistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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11 citing papers in PubMed.
- Enzymatic electrochemiluminescence sensor based on a ternary luminol-HRSC advances · 2026Article
- Nanoconfinement catalysis-enhanced electrochemiluminescence aptasensor for the sensitive detection of matrix metalloproteinase-9.RSC advances · 2026Article
- Enhanced Electrochemiluminescence by Nanocatalyst-Supported Nanochannel-Surfactant Micelle Assembly for Ultrasensitive Detection of Rifampicin.Biosensors · 2026Article
- A low-background, high-output electrochemiluminescence aptasensor for ultrasensitive detection of small biomolecules.Mikrochimica acta · 2026Article
- Triple-enrichment interface enabled by surfactant-modified carbon nanotube for signal-off electrochemiluminescence detection of antitumor drug mitoxantrone.Frontiers in chemistry · 2026Article
- CuFrontiers in chemistry · 2026Article
- Biosensors in dental, oral and craniofacial applications.Npj biosensing · 2026Review
- Sensitive superoxide dismutase detectionRSC advances · 2025Article
- Article
- Enzyme-Based Solid-Phase Electrochemiluminescence Sensors with Stable, Anchored Emitters for Sensitive Glucose Detection.Biosensors · 2025Article
- Sensitive immunosensing of melanoma biomarker based on enhanced electrochemiluminescence via electronic metal-support interactions.Frontiers in chemistry · 2025Article
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3 authors.
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Abstract
As an important inflammatory cytokine, interleukin-6 (IL-6) can mediate the entire pathological process of periodontitis and is closely associated with the degree of inflammation. Therefore, it is critical to develop convenient quantitative methods for monitoring IL-6 quantity in gingival crevicular fluid. In this study, methylene blue (MB)-decorated reduced graphene oxide (rGO) is employed as signal probe to further support the antibody-enabling specific recognition of IL-6. Due to π-π stacking and electrostatic interactions, rGO-MB nanocomposites can be stably obtained. rGO with good conductivity and large surface area characteristics promotes the redox signals of MB on the glassy carbon electrode (GCE). In addition, through the simple
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