Evidence map›Paper›PMID 40242628›Full record

ArticleFrontiers in neurology2025

Comparative analysis of methods for measuring glucocerebrosidase enzyme activity in patients with Parkinson's disease with the

Jin Hwangbo, Myung Jun Lee, Sang Jin Kim, Hyun Kyung Park, Jae-Heyok Lee

Abstract read
In one paragraph

Article in Frontiers in neurology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jin HwangboBusan St. Mary's Hospital, Busan, Republic of Korea.
Myung Jun LeePusan National University Hospital, Busan, Republic of Korea.
Sang Jin KimInje University Busan Paik Hospital, Busan, Republic of Korea.
Hyun Kyung ParkSpecial Chemistry Team, Seoul Clinical Laboratories (SCL), Yongin, Republic of Korea.
Jae-Heyok LeeSchool of Medicine, Pusan National University, Yangsan, Republic of Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Methods: We recruited 25 GBA-PD patients and 27 matched PD patients without Results: No significant differences in demographics or disease characteristics were found between GBA-PD and non-GBA-PD patients. GCase activity was significantly lower in patients with GBA-PD ( Discussion: The relative ratio of GCase activity showed a strong discriminatory potential, distinguishing between GBA-PD and non-GBA-PD.

Indexed as

blood biomarkersGBA1glucocerebrosidaseglycosphingolipidsParkinson’s disease

Identifiers

PMID40242628
PMCPMC11999970

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.