Evidence map›Paper›PMID 40242457›Full record

ArticleFrontiers in neuroscience2025

iTBS over the left hV6A enhances PPC-PPC functional connectivity during reaching tasks: an EEG study.

Jing Chen, Qian Ding, Ya-Wen Li, Yu-Hong Huang, Shan-Tong Yao, Ri-Yu Guo, Long-Ping Wang, Xin-Hua Wei, Yue Lan, Guang-Qing Xu

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Article in Frontiers in neuroscience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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1citing papers in PubMed
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1 · What the graph read from it

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

10 authors.

Jing Chen *School of Rehabilitation Medicine, Shandong Second Medical University, Weifang, China.
Qian Ding *Department of Rehabilitation Medicine, Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou, China.
Ya-Wen Li *Department of Rehabilitation Medicine, Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou, China.
Yu-Hong HuangDepartment of Rehabilitation Medicine, Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou, China.
Shan-Tong YaoDepartment of Rehabilitation Medicine, Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou, China.
Ri-Yu GuoDepartment of Radiology, Guangzhou First People's Hospital, School of Medicine, South China University of Technology, Guangzhou, China.
Long-Ping WangDepartment of Rehabilitation Medicine, Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou, China.
Xin-Hua WeiDepartment of Radiology, Guangzhou First People's Hospital, School of Medicine, South China University of Technology, Guangzhou, China.
Yue LanDepartment of Rehabilitation Medicine, Guangzhou First People's Hospital, School of Medicine, South China University of Technology, Guangzhou, China.
Guang-Qing XuDepartment of Rehabilitation Medicine, Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: The functional connectivity of the posterior parietal cortex-primary motor cortex (PPC-M1) is involved in goal-directed reaching actions and integrating visuomotor transformation. Human area V6A (hV6A), located in the medial PPC, is a critical node of the dorsomedial system that is involved in targeting during reaching movements. Here, we used Electroencephalography (EEG) to investigate functional connectivity and network efficiency during right-hand reaching tasks after inducing left hV6A activity with intermittent theta burst stimulation (iTBS). Methods: Based on individualized MRI neural navigation, 23 healthy subjects were randomly accepted into either real left hV6A or sham iTBS on 2 days. Resting-state and goal-directed reaching task EEG were recorded at baseline and immediately after iTBS to assess the effects of iTBS on functional connectivity. Alongside the reaching task, an additional Stroop test was conducted to assess each participant's degree of attention. Results: In the alpha band, medial posterior parietal cortical interhemispheric functional connectivity significantly increased during right-hand reaching tasks after hV6A iTBS ( Discussions: Functional connectivity of the bilateral PPC and functional network efficiency increased after iTBS of the left hV6A during right-hand reaching tasks. These findings indicate that the left hV6A should be a potential target for iTBS modulation to improve the orienting movement function in space.

Indexed as

functional neuroimagingposterior parietal cortexreachingtranscranial magnetic stimulationV6A

Identifiers

PMID40242457
PMCPMC12001803

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.