ArticleReports of practical oncology and radiotherapy : journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation Oncology2025
Evaluation of dose distributions in the overlapping regions of the modulated volumetric arcs used in total body irradiation in pediatric patients.
Article in Reports of practical oncology and radiotherapy : journal of Greatpoland Cancer Center in Poznan and Polish Society of Radiation Oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- End-to-end technical validation of multi-isocenter total body irradiation using an anthropomorphic phantom.Radiological physics and technology · 2026Article
- Total body irradiation (TBI) combining volumetric modulated arc therapy (VMAT) for thorax at standard source axis distance (SAD) with intensity modulated radiation therapy (IMRT) at extended SAD.Journal of applied clinical medical physics · 2026Article
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18 authors.
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Abstract
Background: The application of total body irradiation (TBI), using intensity-modulated techniques with dynamic arcs, creates overlap at the treatment arc boundaries, which can lead to dosimetric variations. Therefore, this research aimed to evaluate the dose distributions in the overlap regions of the arcs used in total body irradiation in pediatric patients. Material and methods: This dosimetric evaluation was conducted on a CIRS 715-TY0710 pediatric body simulator, where a treatment plan with three isocenters was designed, generating two 4 cm overlap regions along the line connecting the isocenters. The plan was verified using the gamma criteria of 3%/3mm and 5%/5mm with the Octavius 4D software. Results and Conclusions: The planning results showed 98.2% dose coverage over 95% of the planning target volume (PTV) with adequate tolerance for risk organs. Regarding the gamma analysis, the acceptance rate was greater than 95% at the treatment isocenters with criteria of 3%/3 mm and 5%/5 mm. However, there is a decrease in the approved points in the overlap zone when evaluated with a 3%/3 mm criterion, while maintaining an approval percentage above 95% when evaluated with a 5%/5 mm criterion.
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