Evidence map›Paper›PMID 40242299›Full record

ArticleACG case reports journal2025

Successful Use of a Novel High-Dose Mycophenolate Mofetil and Rituximab Regimen for Progressive IgG4 Sclerosing Cholangitis With Multisystemic Involvement.

Ujwala Pamidimukkala, Gabriella Aitcheson, Hala Fatima, Itegbemie Obaitan

Abstract readCase Reports
In one paragraph

Article in ACG case reports journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ujwala PamidimukkalaIndiana University School of Medicine, Indianapolis, IN.ORCID https://orcid.org/0000-0002-2652-8853
Gabriella AitchesonDivision of Gastroenterology and Hepatology, Indiana University School of Medicine, Indianapolis, IN.
Hala FatimaDivision of Gastroenterology and Hepatology, Indiana University School of Medicine, Indianapolis, IN.
Itegbemie ObaitanDivision of Gastroenterology and Hepatology, Indiana University School of Medicine, Indianapolis, IN.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Immunoglobulin G4 (IgG4) sclerosing cholangitis is an immune-mediated fibroinflammatory disease of the biliary tree. It may be asymptomatic or cause abdominal pain, jaundice, or pruritus on presentation. While glucocorticoids and rituximab are regarded as initial treatment options, there is little guidance on the management of patients who either cannot tolerate these agents or are refractory to them. We discuss a case of IgG4 sclerosing cholangitis that required a novel treatment strategy of 1,000 mg oral mycophenolate mofetil twice daily and 375 mg/m

Indexed as

IgG4 sclerosing cholangitisimmunosuppressionsystemic involvement

Identifiers

PMID40242299
PMCPMC12002363

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.