Evidence map›Paper›PMID 40242184›Full record

ArticleThe Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale2025

Thymopoietin-

Víctor Huerta-Padilla, Daniel Marrero-Rodríguez, Keiko Taniguchi-Ponciano, Ariana E López, Fernando Candanedo-González, Emmanuel Salcedo, Alejandra Valdivia-Flores, Miriam Rodriguez-Esquivel, Laura Gómez Virgilio, Ricardo López-Romero and 5 more

Abstract read
In one paragraph

Article in The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Bioinformatics insights intoFrontiers in cell and developmental biology · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Víctor Huerta-PadillaOncology Genomics Biomedical Research Unit, Gynecology Pediatrics Hospital 3A, North Unity OOAD, Mexican Institute of Social Security, Mexico City, Mexico.ORCID https://orcid.org/0009-0003-8843-7038
Daniel Marrero-RodríguezEndocrine Diseases Research Unit, Specialties Hospital, National Medical Center SXXI, Mexican Institute of Social Security, Mexico City, Mexico.ORCID https://orcid.org/0000-0001-5311-6654
Keiko Taniguchi-PoncianoEndocrine Diseases Research Unit, Specialties Hospital, National Medical Center SXXI, Mexican Institute of Social Security, Mexico City, Mexico.ORCID https://orcid.org/0000-0003-1623-7398
Ariana E LópezOncology Genomics Biomedical Research Unit, Gynecology Pediatrics Hospital 3A, North Unity OOAD, Mexican Institute of Social Security, Mexico City, Mexico.
Fernando Candanedo-GonzálezAnatomo-Pathology Service, Oncology Hospital, National Medical Center SXXI, Mexican Institute of Social Security, Mexico City, Mexico.ORCID https://orcid.org/0000-0002-6926-8182
Emmanuel SalcedoOncology Genomics Biomedical Research Unit, Gynecology Pediatrics Hospital 3A, North Unity OOAD, Mexican Institute of Social Security, Mexico City, Mexico.
Alejandra Valdivia-FloresEscuela Nacional de Ciencias Biologicas, Instituto Politecnico Nacional, Mexico City, Mexico.ORCID https://orcid.org/0000-0002-0574-5111
Miriam Rodriguez-EsquivelOncology Genomics Biomedical Research Unit, Gynecology Pediatrics Hospital 3A, North Unity OOAD, Mexican Institute of Social Security, Mexico City, Mexico.ORCID https://orcid.org/0000-0003-2184-300X
Laura Gómez VirgilioCentro de Investigación y de Estudios Avanzados, Molecular Biomedicine Department, Instituto Politecnico Nacional, Mexico City, Mexico.ORCID https://orcid.org/0000-0001-7765-8159
Ricardo López-RomeroOncology Genomics Biomedical Research Unit, Gynecology Pediatrics Hospital 3A, North Unity OOAD, Mexican Institute of Social Security, Mexico City, Mexico.ORCID https://orcid.org/0000-0002-5030-5836
Maria de Jesus Nambo-LucioLondres Clinic, Angels Hospital, Ciudad de Mexico, Mexico.ORCID https://orcid.org/0000-0001-5582-6895
Sergio E Meza-ToledoDepartamento de Bioquimica, Laboratorio de Quimioterapia Experimental, Escuela Nacional de Ciencias Biológicas, Instituto Politecnico Nacional, Mexico City, Mexico.ORCID https://orcid.org/0000-0003-0447-7642
Cindy BandalaDepartamento de Medicina Traslacional aplicada a Neurociencias, Escuela Superior de Medicina, Instituto Politecnico Nacional, Mexico City, Mexico.ORCID https://orcid.org/0000-0002-7414-2621
Marco A MerazCentro de Investigación y de Estudios Avanzados, Molecular Biomedicine Department, Instituto Politecnico Nacional, Mexico City, Mexico.ORCID https://orcid.org/0000-0001-6748-8117
Mauricio SalcedoOncology Genomics Biomedical Research Unit, Gynecology Pediatrics Hospital 3A, North Unity OOAD, Mexican Institute of Social Security, Mexico City, Mexico.ORCID https://orcid.org/0000-0002-9978-6511

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cervical cancer (CC) is a public health concern related to the human papillomavirus (HPV) persistent infection. Minichromosome maintenance 2 (MCM2) has been postulated as a surrogate marker for HPV infection. Thymopoietin (TMPO) is a nuclear protein regulated by E2F such as MCM2 or p16. TMPO can give rise to six different isoforms. Herein, both the mRNA and protein levels of TMPO isoforms were analyzed in cervical cells. TMPO expression was selected and analyzed through in silico in several databases from the healthy cervix and cervical lesions. TMPO RNA expression was evaluated in cervical samples and cell lines by RT-PCR and protein expression by Western-blot and immunohistochemistry assays. TMPO and MCM2 immunostaining were evaluated in cervical smears. The clinical-pathological correlation analysis was performed using Kruskal-Wallis or

Indexed as

cervical cancerexpressionHPVisoformsMCM2thymopoietin

Identifiers

PMID40242184
PMCPMC12003041

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.