Evidence map›Paper›PMID 40242060›Full record

ArticleOpen forum infectious diseases2025

Unrecognized Tuberculosis: Risk Factors for Smear-Positive/Cavitary Asymptomatic Cases.

Jee Youn Oh, Timothy C Rodwell, Rehan R Syed, Yousang Ko, Jinsoo Min, Hyung Woo Kim, Hyeon-Kyoung Koo, Yun-Jeong Jeong, Eun Hye Lee, Bumhee Yang and 8 more

Abstract read
In one paragraph

Article in Open forum infectious diseases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Jee Youn OhDivision of Pulmonary, Allergy, and Critical Care Medicine, Department of Internal Medicine, Korea University College of Medicine, Korea University Republic of Korea, Guro Hospital, Seoul, Republic of Korea.ORCID https://orcid.org/0000-0002-1219-0070
Timothy C RodwellDivision of Pulmonary, Critical Care, Sleep Medicine & Physiology, University of California, San Diego, La Jolla, California, USA.ORCID https://orcid.org/0000-0003-2779-3197
Rehan R SyedDivision of Infectious Diseases and Global Public Health, University of California, San Diego, La Jolla, California, USA.ORCID https://orcid.org/0000-0001-8898-7388
Yousang KoDivision of Pulmonary, Allergy and Critical Care Medicine, Department of Internal Medicine, Hallym University Kangdong Sacred Heart Hospital, Seoul, Republic of Korea.
Jinsoo MinDivision of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.ORCID https://orcid.org/0000-0001-6091-518X
Hyung Woo KimDivision of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Incheon St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Incheon, Republic of Korea.
Hyeon-Kyoung KooDivision of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Ilsan Paik Hospital, Inje University College of Medicine, Ilsan, Republic of Korea.
Yun-Jeong JeongDivision of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Dongguk University Ilsan Hospital, Ilsan, Republic of Korea.
Eun Hye LeeDivision of Pulmonology, Allergy and Critical Care Medicine, Department of Internal Medicine, Yongin Severance Hospital, Yonsei University College of Medicine, Yongin, Republic of Korea.
Bumhee YangDivision of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Chungbuk National University Hospital, Chungbuk National University College of Medicine, Cheong-Ju, Republic of Korea.
Ganghee ChaeDivision of Pulmonology and Critical Care Medicine, Department of Internal Medicine, Ulsan University Hospital, University of Ulsan College of Medicine, Ulsan, Republic of Korea.ORCID https://orcid.org/0000-0002-7480-2634
Ju Sang KimDivision of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Incheon St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Incheon, Republic of Korea.
Sung-Soon LeeDivision of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Ilsan Paik Hospital, Inje University College of Medicine, Ilsan, Republic of Korea.
Hun-Gyu HwangRespiratory Division, Department of Internal Medicine, Soonchunhyang University Gumi Hospital, Soonchunhyang University School of Medicine, Gumi, Korea.
Jaehee LeeDepartment of Internal Medicine, School of Medicine, Kyungpook National University, Daegu, Republic of Korea.ORCID https://orcid.org/0000-0001-8111-7320
Heung Bum LeeDepartment of Internal Medicine, Jeonbuk National University Medical School, Jeonju, Republic of Korea.ORCID https://orcid.org/0000-0002-8267-8434
Juock NaDivision of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Cheonan Hospital, Soonchunhyang University College of Medicine, Cheonan, Republic of Korea.
Jae Seuk ParkDivision of Pulmonary Medicine, Department of Internal Medicine, Dankook University College of Medicine, Cheonan, Republic of Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Screening patients with asymptomatic active tuberculosis (TB) is crucial as they can transmit the disease. Identifying the risk factors for transmission is essential for targeted screening. Understanding how the infectiousness of asymptomatic patients with TB affects disease outcomes is crucial for developing strategies to control TB spread. Methods: We analyzed the national Korean TB cohort data to determine the factors associated with transmission risk and clinical outcomes in patients with asymptomatic pulmonary TB. The primary outcome was the factors associated with a risk factor for transmission, while the secondary outcome was mortality in asymptomatic patients with pulmonary TB stratified by transmission risk. Results: Among 20 455 patients with pulmonary TB, 7434 (36.4%) were asymptomatic, while 1520 (25.5%) had potential transmission risks, indicated by a positive sputum acid-fast bacillus smear test or cavitation on chest radiographs. The factors associated with a higher transmission risk included male sex (odds ratio [OR], 1.385; 95% CI, 1.172-1.636; Conclusions: Lean, smoking men with asymptomatic TB who have DM and/or autoimmune diseases have higher transmission and mortality risk. Asymptomatic populations with these risk factors warrant targeted screening.

Indexed as

asymptomaticcohort studiespulmonarytransmissiontuberculosis

Identifiers

PMID40242060
PMCPMC12000806

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.