ArticleJournal of orthopaedics2025
Developing and analyzing a Nanocomposites coated material for hammertoe implants.
Article in Journal of orthopaedics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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4 authors.
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Abstract
Hammertoe implants, frequently used for arthroplasty or proximal interphalangeal joint arthrodesis, have serious drawbacks because of bacterial colonization and material corrosion, which can result in infections and other problems. This study creates a new nanocomposite covering to improve the corrosion resistance, antibacterial qualities, and biocompatibility of 316L stainless steel (SS). 316L SS was treated with a nanocomposite made of graphene oxide (GO), zirconia (ZrO₂), and hydroxyapatite (HAp). The coating's structural and functional characteristics were examined using Fourier-transform infrared spectroscopy (FTIR), scanning electron microscopy (SEM), and energy-dispersive X-ray spectroscopy (EDX). Standard assays were used to evaluate the coated material's antibacterial activity, and simulated bodily fluid (SBF) was used to assess corrosion resistance in vitro. Biocompatibility was verified using assays for cell survival. Apatite layer formation during SBF immersion indicated increased bioactivity and the results showed that the HAp-ZrO₂-GO nanocomposite coating greatly increased the corrosion resistance of 316L SS. The coating showed anti-inflammatory and potent antibacterial qualities, successfully preventing bacterial colonization. Additionally, cell survival tests verified the coated material's biocompatibility, indicating that it would be safe for use in biomedical applications. This work presents a scalable and reasonably priced process for creating bioactive nanocomposite coatings for medical implants. The HAp-ZrO₂-GO coating addresses important drawbacks of conventional implant materials by improving physico-chemical interactions and providing better performance. With significant ramifications for developing biomedical engineering and enhancing patient outcomes, these results demonstrate the potential of the HAp-ZrO₂-GO nanocomposite as a workable option for long-lasting, antimicrobial, and biocompatible bioimplant coatings.
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