ArticleJournal of pain research2025
The Relationship Between Psychosocial Factors and Response to Epidural Steroid Injection for Chronic Lumbosacral Radicular Pain: A Prospective Pilot Study.
Article in Journal of pain research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
2 citing papers in PubMed.
- Ten Years of Lumbar Transforaminal Epidural Steroid Injections in a Tertiary Referral Center: Trends in Clinical Indications and Outcomes.Pain practice : the official journal of World Institute of Pain · 2026Article
- Prevalence of psychological comorbidities and their association with injection therapy outcomes in patients with chronic low back pain: a registry-based retrospective cohort study.Frontiers in medicine · 2026Article
Corrections and comments
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Authors and funding
17 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Purpose: Chronic lumbosacral radicular pain is a disabling condition commonly treated with epidural steroid injections (ESIs). Extant research suggests that psychosocial factors impact clinical outcomes among patients with back pain. The purpose of this study is to examine the relationship between psychosocial variables and post-injection pain intensity. Setting: Interventional pain management clinic. Methods: A prospective longitudinal cohort study with repeated within-subject measures. Assessment timepoints included a pre-injection baseline, immediately post-injection, 6 weeks, and 12 weeks, and 6 months; patients completed a battery of self-report assessments at each point. The primary outcome was pain intensity (numeric rating scale 0-10). Data were analyzed using principal component analysis and generalized linear mixed-effects modeling. Results: A total of 40 patients (age 52 ±13.05) participated in this study. Higher pre-injection pain was predictive of higher post-injection pain at all time points ( Conclusion: Patients with higher negative affect and lower cognitive resilience achieve less pain improvement after ESIs for low back pain. Future research with a larger sample should focus on deepening our understanding of the role of psychosocial functioning as a potential mechanism of treatment response in patients undergoing ESI procedures. Findings point to the importance of multidisciplinary chronic pain care.
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