Evidence map›Paper›PMID 40241757›Full record

ArticleiScience2025

Emergence of natural and robust bipedal walking by learning from biologically plausible objectives.

Pierre Schumacher, Thomas Geijtenbeek, Vittorio Caggiano, Vikash Kumar, Syn Schmitt, Georg Martius, Daniel F B Haeufle

Abstract read
In one paragraph

Article in iScience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. [Progress and application of machine learning in sports injury research].Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi · 2026
    Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Pierre SchumacherMax-Planck Institute for Intelligent Systems, Tübingen, Germany.
Thomas GeijtenbeekGoatstream, Delft, the Netherlands.
Vittorio CaggianoMeta AI, New York, New York, USA.
Vikash KumarMeta AI, New York, New York, USA.
Syn SchmittInstitute for Modelling and Simulation of Biomechanical Systems, University of Stuttgart, Stuttgart, Germany.
Georg MartiusMax-Planck Institute for Intelligent Systems, Tübingen, Germany.
Daniel F B HaeufleHertie Institute for Clinical Brain Research and Center for Integrative Neuroscience, Tübingen, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Humans show unparalleled ability when maneuvering diverse terrains. While reinforcement learning (RL) has shown great promise for musculoskeletal simulation in the development of robust controllers, complex behaviors are only achievable under extensive use of motion data. We demonstrate that the combination of a recent RL algorithm with a biologically plausible reward is capable of learning controllers for 4 different musculoskeletal models and achieves locomotion with up to 90 muscles without demonstrations. Our controllers generalize to diverse and unseen terrains, while only a single adaptive objective function is needed for training. We validate our findings on four models in two different simulators. The RL agents perform robustly with complex 3D models, where reflex-controllers are difficult to apply, and produce close-to-natural motion. This is a first step for the motor control, biomechanics, and rehabilitation communities to generate complex human movements with RL, without using motion data or simple unrepresentative models.

Indexed as

Behavioral neuroscienceBiological sciencesNeuroscience

Identifiers

PMID40241757
PMCPMC12002607

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.