Evidence map›Paper›PMID 40241756›Full record

ArticleiScience2025

Somatic

Jhonatan Henao Vasquez, Jin Yuan, Chi Jing Leow, Erin Crossey, Fengzhi Shao, Senegal Carty, Viviana A Dominguez, Ming Lo, Joseph P Mizgerd, Jessica L Fetterman and 3 more

Abstract read
In one paragraph

Article in iScience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Jhonatan Henao VasquezThe Pulmonary Center, Boston University Chobanian & Avedisian School of Medicine, Boston, MA 02118, USA.
Jin YuanThe Pulmonary Center, Boston University Chobanian & Avedisian School of Medicine, Boston, MA 02118, USA.
Chi Jing LeowDepartment of Biochemistry and Cell Biology, Boston University Chobanian & Avedisian School of Medicine, Boston, MA 02118, USA.
Erin CrosseyThe Pulmonary Center, Boston University Chobanian & Avedisian School of Medicine, Boston, MA 02118, USA.
Fengzhi ShaoThe Pulmonary Center, Boston University Chobanian & Avedisian School of Medicine, Boston, MA 02118, USA.
Senegal CartyThe Pulmonary Center, Boston University Chobanian & Avedisian School of Medicine, Boston, MA 02118, USA.
Viviana A DominguezDepartment of Medicine, Boston University Chobanian & Avedisian School of Medicine, Boston, MA 02118, USA.
Ming LoNational Emerging Infectious Diseases Laboratories, Comparative Pathology Laboratory, Boston University Chobanian & Avedisian School of Medicine, Boston, MA 02118, USA.
Joseph P MizgerdThe Pulmonary Center, Boston University Chobanian & Avedisian School of Medicine, Boston, MA 02118, USA.
Jessica L FettermanDepartment of Medicine, Boston University Chobanian & Avedisian School of Medicine, Boston, MA 02118, USA.
Nelson C LauDepartment of Biochemistry and Cell Biology, Boston University Chobanian & Avedisian School of Medicine, Boston, MA 02118, USA.
Alan FineThe Pulmonary Center, Boston University Chobanian & Avedisian School of Medicine, Boston, MA 02118, USA.
Matthew R JonesThe Pulmonary Center, Boston University Chobanian & Avedisian School of Medicine, Boston, MA 02118, USA.

Funding

Pulmonary pathophysiology sub-phenotypes of pneumoniaR01AI162850 · NIAID · BOSTON UNIVERSITY MEDICAL CAMPUS · PI JOSEPH P MIZGERD · 2022 to 2026
$4.0M
Transposable Element (TE) RNA regulation via small RNA pathways in aging cells and neurodegeneration.R01AG078930 · NIA · BOSTON UNIVERSITY MEDICAL CAMPUS · PI NELSON C LAU · 2022 to 2026
$3.5M
Fibrin in the Infected LungR01HL171499 · NHLBI · BOSTON UNIVERSITY MEDICAL CAMPUS · PI JOSEPH P MIZGERD · 2024 to 2026
$2.3M
The interplay between transposons and piRNA pathways.R01GM135215 · NIGMS · BOSTON UNIVERSITY MEDICAL CAMPUS · PI LAU, NELSON C · 2020 to 2023
$1.8M
NHLBI NIH HHS R01 HL171499NIAID NIH HHS R01 AI162850NIA NIH HHS R01 AG078930NIGMS NIH HHS R01 GM135215
6 · The paper itself

Abstract

MIWI2, a P element-induced wimpy testes (PIWI) argonaute protein known for suppressing retrotransposons during male gonadogenesis, has an unexplored role in mammalian somatic cells. We identify MIWI2 multiciliated (M2MC) cells as a rare subset of airway multiciliated cells and investigate MIWI2's function in antiviral host defense. We analyzed transcriptomes from

Indexed as

BiochemistryCell biologyFunctional aspects of cell biology

Identifiers

PMID40241756
PMCPMC12002665

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.