ArticleFrontiers in microbiology2025
Advancing aquaculture probiotic discovery via an innovative protocol for isolation of indigenous, heat and salt tolerant, quorum quenching probiotic candidates.
Article in Frontiers in microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed.
- Isolation, Characterization and Molecular Identification of Putative Probiotic Bacteria From Red Tilapia Gut.Environmental microbiology reports · 2026Article
- The Invisible Balance: How Prebiotics and Probiotics Can Support Fish Health and Development.Life (Basel, Switzerland) · 2026Review
- An Aeromonad selectively removes a class of pathogens from shrimp, prevents disease and preserves a healthy commensal microbiome.bioRxiv : the preprint server for biology · 2026Article
- A Novel Lactococcus Lactis LZK-02 Strain Antagonistic to Staphylococcus Aureus: In Vitro Probiotic Profiling and in Vivo Benefits as Feed Additive in Micropterus Salmoides.Probiotics and antimicrobial proteins · 2026Article
- Quorum-quenching for bacterial pathogen control and health management in aquaculture: mechanisms, applications, current status and future prospects.Frontiers in systems biology · 2026Review
- Succession of the yellow tang (PeerJ · 2026Article
- Phenotypic and safety exploration of indigenous bacterial strains for probiotic applications in aquaculture.BMC microbiology · 2025Article
- Genomic Characterization of Four Novel Probiotic Strains with Enzymatic Activity and Their Effects on Carp (Animals : an open access journal from MDPI · 2025Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Introduction: The intensification of aquaculture to meet the growing demand for aquatic animal protein by a global population approaching 10 billion by 2050 has raised concerns about the increased risk of disease outbreaks in farmed species. These diseases account for over 50% of economic losses in commercial aquaculture, largely due to the reliance on ineffective and harmful therapeutic options like antibiotics, which contribute to multidrug resistance and pose serious global health concerns. However, non-antibiotic alternatives such as probiotics have emerged promising choices to enhance growth performance, immunity, and disease resistance in aquaculture species. Methods: In this study, we present a novel, non-invasive protocol for isolating indigenous bacteria from sediment. This method utilizes minimal media supplemented with N-hexanoyl homoserine lactone (HHL) to select strains with key probiotic attributes. Results and discussion: Our study isolated 24 bacterial isolates, 11 demonstrating quorum quenching (QQ) activity by degrading HHL, indicating potential for antivirulence therapy. Among these, eight were non-hemolytic, suggesting safety in the presence of host wounds. Six non-hemolytic isolates exhibited proteolytic activity, which is essential for aiding protein digestion. Whole genome sequencing revealed their identity as
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