Evidence map›Paper›PMID 40241517›Full record

ArticleScience progress

Effect of cucurbit[7]uril on DPPC-containing liposomes: Interactions with the lipid bilayer.

Summay Altaher, Walhan Alshaer, Fedaa Al Adaileh, Hamdi Nsairat, Shrouq Alsotari, Majdoleen H Rababah, Abeer Al Bawab, Fadwa Odeh

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Science progress. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Summay AltaherDepartment of Chemistry, The University of Jordan, Amman, Jordan.ORCID 0000-0001-5087-8151
Walhan AlshaerCell Therapy Center, The University of Jordan, Amman, Jordan.ORCID 0000-0003-2946-7328
Fedaa Al AdailehDepartment of Chemistry, The University of Jordan, Amman, Jordan.ORCID 0000-0003-3502-526X
Hamdi NsairatPharmacological and Diagnostic Research Center, Faculty of Pharmacy, Al-Ahliyya Amman University, Amman, Jordan.ORCID 0000-0001-5916-5879
Shrouq AlsotariCell Therapy Center, The University of Jordan, Amman, Jordan.ORCID 0009-0004-7895-7993
Majdoleen H RababahDepartment of Chemistry, The University of Jordan, Amman, Jordan.ORCID 0009-0004-3557-7923
Abeer Al BawabDepartment of Chemistry, The University of Jordan, Amman, Jordan.ORCID 0000-0003-2131-1791
Fadwa OdehDepartment of Chemistry, The University of Jordan, Amman, Jordan.ORCID 0000-0002-9341-2359

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Liposomes, which are bilayer lipidic nanocarriers, have been utilized in many pharmaceutical applications to enhance the solubility and therapeutic index of drugs. Liposomes have also been used as carriers for smaller drug carriers, such as cucurbiturils, to achieve a more controlled release of the drug into the targeted site in the body. In this study, we investigated the effects of cucurbit[7]uril, a macrocyclic organic compound, on the integrity of liposome lipid membranes. The average liposome size, measured by dynamic light scattering, increased with increasing concentrations of cucurbit[7]uril. In addition, fluorescence spectroscopy was used to calculate an association constant (

Indexed as

1,2-DipalmitoylphosphatidylcholineBridged-Ring CompoundsImidazolesLipid BilayersLiposomesCholesterolCucurbit(n)urilsHeterocyclic Compounds, 2-RingHumansImidazolidinesMacrocyclic CompoundsParticle Size1,2-DipalmitoylphosphatidylcholineBridged-Ring CompoundsCholesterolcucurbit(7)urilCucurbit(n)urilsHeterocyclic Compounds, 2-RingImidazolesImidazolidinesLipid BilayersLiposomesMacrocyclic CompoundsCholesterolcucurbit[7]urilhemolysisliposomestability

Identifiers

PMID40241517
PMCPMC12035499

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.