Evidence map›Paper›PMID 40241335›Full record

ReviewAngewandte Chemie (International ed. in English)2025

An Update: Enzymatic Synthesis for Industrial Applications.

Thomas Bayer, Shuke Wu, Radka Snajdrova, Kai Baldenius, Uwe T Bornscheuer

Abstract readReview
In one paragraph

Review in Angewandte Chemie (International ed. in English), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed.

  1. Review
  2. Next-Generation Manufacturing: The Evolving Role of Biocatalysis in AstraZeneca.Chembiochem : a European journal of chemical biology · 2026
    Review
  3. Article
  4. Article
  5. Review
  6. Article
  7. Review
  8. Review
  9. Asymmetric Reduction of Unactivated Alkenes.Chemistry (Weinheim an der Bergstrasse, Germany) · 2026
    Review
  10. Article
  11. DNA Flap-Mediated Control of Transcription for Programmable RNA Synthesis.Angewandte Chemie (International ed. in English) · 2026
    Article
  12. Article
  13. Article
  14. Biocatalytic Regioselective C-Formylation of Resorcinol Derivatives.Angewandte Chemie (International ed. in English) · 2026
    Article
  15. Article
  16. Review
  17. Article
  18. Article
  19. Protein engineering: status report.Protein engineering, design & selection : PEDS · 2026
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Thomas BayerInstitute of Biochemistry, Dept. of Biotechnology & Enzyme Catalysis, Greifswald University, Felix-Hausdorff-Str. 4, 17487, Greifswald, Germany.
Shuke WuNational Key Laboratory of Agricultural Microbiology, College of Life Science and Technology, Huazhong Agricultural University, 1 Shizishan Street, Wuhan, 430070, P.R. China.
Radka SnajdrovaNovartis Institutes for BioMedical Research, Global Discovery Chemistry, Basel, 4056, Switzerland.
Kai BaldeniusBaldenius Biotech Consulting, Hafenstr. 31, 68159, Mannheim, Germany.
Uwe T BornscheuerInstitute of Biochemistry, Dept. of Biotechnology & Enzyme Catalysis, Greifswald University, Felix-Hausdorff-Str. 4, 17487, Greifswald, Germany.

Funding

Deutsche Forschungsgemeinschaft NFDI/2-1-2021National Natural Science Foundation of China 22378155National Natural Science Foundation of China 32101229
6 · The paper itself

Abstract

Supported by rapid technological advancements, biocatalytic applications have matured into sustainable, scalable, and cost-competitive alternatives to established chemical catalysis. This review presents the most recent examples of enzyme-based solutions for the manufacturing of molecules with extended carbon-carbon frameworks and multiple stereogenic centers at commercial scale, including peptide building blocks, (rare) sugars, synthetic (oligo)nucleotides, and terpenoids, such as (-)-Ambrox

Indexed as

EnzymesBiocatalysisDNAPeptidesRNATerpenesDNAEnzymesPeptidesRNATerpenesBiocatalysisEnzyme catalysisIndustrial catalysisOrganic synthesisStereoselectivity

Identifiers

PMID40241335
PMCPMC12207387

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.