ArticleBMC research notes2025
New burn model for developing consistent second- and third-degree burn injuries in rats.
Article in BMC research notes, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Experimental Burn Induction in Laboratory Animals: A Scoping Review of Methods, Reproducibility, Operator-Dependent Variability, and Relevance to Soft Tissue Reconstruction and Repair.Bioengineering (Basel, Switzerland) · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThis study's aim was: (1) introduce the digital drying oven as a reproducible, controllable, and accurate heating device for burn model creation. (2) Define the heating temperature appropriate for developing consistent second and third-degree burn injuries in rats.
resultsBurns appeared deeper with more distinct borders in groups (B) and (C) than in group (A). The stainless-steel rod at 100 ºC created burn injuries of the second degree, evidenced by the sloughing of the epidermis and necrosis in the epithelium and upper part of the dermis. Heating at 150 and 200 ºC created third-degree burn injuries, where necrosis involved the epidermis and dermis and extended to the subcutaneous fat and muscles. The depth of the burn wound in the group (B) (371.2 ± 41.3 μm) and (C) (385.2 ± 38.0 μm) was significantly deeper compared with the group (A) (178 ± 46.6 μm) (P < 0.001). The digital drying oven is a reliable, reproducible, and controllable heating device for creating burn models. The stainless-steel rod (63 g and 8 mm) heated at 100 and 150 ºC with a contact time of 30 s is adequate for creating consistent second and third-degree burn injuries in rats, respectively.
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Registered trials
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