Evidence map›Paper›PMID 40241096›Full record

ArticleBMC musculoskeletal disorders2025

Effects of an additional multimodal intervention (MultiMove) during inpatient rehabilitation on clinical and functional outcomes in patients with chronic low back pain- a pilot trial.

Toan Nguyen, Martin Behrens, Kim-Charline Broscheid, Robert Bielitzki, Kerstin Rohkohl, Ivonne Rudolph, Katharina Meiler, Jörg Franke, Lutz Schega

Abstract readControlled Clinical Trial
In one paragraph

Article in BMC musculoskeletal disorders, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Toan Nguyen *Department of Sport Science, Institute III, Otto von Guericke University Magdeburg, Magdeburg, Germany.
Martin Behrens *University of Applied Sciences for Sport and Management Potsdam, Olympischer Weg 7, 14471, Potsdam, Germany. dr.martin.behrens@outlook.de.
Kim-Charline BroscheidDepartment of Sport and Exercise Medicine, Institute of Movement Science and Psychology, University of Hamburg, Hamburg, Germany.
Robert BielitzkiDepartment of Sport Science, Institute III, Otto von Guericke University Magdeburg, Magdeburg, Germany. robert.bielitzki@ovgu.de.
Kerstin RohkohlRehabilitation Clinic Bad Salzelmen, Waldburg Zeil Clinics, Schönebeck, Germany.
Ivonne RudolphRehabilitation Clinic Bad Salzelmen, Waldburg Zeil Clinics, Schönebeck, Germany.
Katharina MeilerDepartment of Orthopedic Surgery, Klinikum Magdeburg gGmbH, Magdeburg, Germany.
Jörg FrankeDepartment of Orthopedic Surgery, Klinikum Magdeburg gGmbH, Magdeburg, Germany.
Lutz SchegaDepartment of Sport Science, Institute III, Otto von Guericke University Magdeburg, Magdeburg, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAs a leading cause of disability, chronic low back pain (CLBP) is a musculoskeletal condition often associated with impaired physical and cognitive functions. Due to its multi-factorial facets, the application of multimodal interventions is recommended. MultiMove is a multimodal intervention designed for CLBP patients, which combines motor-cognitive and dancing exercises. This study aimed to assess the effects of an additional MultiMove intervention to a standard inpatient rehabilitation on clinical and functional outcomes in CLBP patients.

methodsFor this prospective, two-arm, controlled pilot trial, 27 CLBP patients (17 females, 10 males) undergoing a 3-week inpatient rehabilitation, in a rehabilitation clinic in Germany, were recruited. The intervention group (IG, n = 15, 61.6 ± 1.8 years) received a daily MultiMove session in addition to the standard rehabilitation, while the control group (CG, n = 12, 63.8 ± 2.2 years) followed the standard rehabilitation. Physical (Timed Up and Go (TUG) [primary outcome], Five-Repetition Sit-to-Stand (FRSTS), and Six-Minute Walk Test (6MWT), trunk range of motion, single and dual task walking)), clinical (acute/chronic pain intensity, Oswestry Disability Index, EQ-5D-5 L), cognitive (Stroop Color Word Test, Trail Making Test), and psychosocial outcomes (Tampa Scale of Kinesiophobia, Beck Depression Inventory-II, Coping Strategies Questionnaire) were assessed during the first (pre-test) and last day (post-test) of the inpatient rehabilitation.

resultsThe statistical analyses revealed improvements in trunk range of motion (sagittal plane: p = 0.018, d = 1.00; transversal plane: p = 0.006, d = 1.18) and 6MWT performance (p = 0.003, d = 1.30) in the IG compared to the CG. Moreover, lower dual task costs for a gait variability measure (p = 0.034, d = 0.97) as well as reduced chronic pain intensity (p = 0.004, d = 1.33), kinesiophobia (p = 0.035, d = 1.15), and depression (p = 0.034, d = 1.08) were found in favour of the IG.

conclusionData indicate that the multimodal intervention MultiMove improved clinical and functional outcomes in CLBP patients during inpatient rehabilitation. Therefore, conducting a randomized controlled trial with a large sample size is recommended to verify and extent these results.

trial registrationMultiMove project (German Clinical Trial Register, ID: DRKS00021696 / 10.07.2020, https://drks.de/drks_web/navigate.do?navigationId=trial.HTML26TRIAL_ID=DRKS00021696 ) and was carried out in the rehabilitation clinic Bad Salzelmen (Schönebeck, Germany).

Indexed as

Chronic PainExercise TherapyLow Back PainAgedCombined Modality TherapyFemaleGermanyHumansInpatientsMaleMiddle AgedPain MeasurementPilot ProjectsProspective StudiesRecovery of FunctionTreatment OutcomeCognitive functionsDancingDepressionFunctional mobilityKinesiophobiaPhysical functionsQuality of lifeWalking

Identifiers

PMID40241096
PMCPMC12001476

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.