Evidence map›Paper›PMID 40241071›Full record

ArticleBMC cancer2025

Advancing the implementation of quality-assured oncological exercise therapy in Germany: protocol for the IMPLEMENT project.

Mirko Brandes, Anika Berling-Ernst, Hansjoerg Baurecht, Wiebke Jensen, Miriam Götte, Anne Herrmann, Daniela Fuhr, Heike Schmidt, Antonia Lucas, Bernardine Madl and 23 more

Registry-linked trialAbstract readClinical Trial Protocol
In one paragraph

Article in BMC cancer, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06496711 (IMPLEMENT - Model Project for the Cross-sector Implementation of a Comprehensive and Quality-assured Sports and Exercise Therapy for Cancer Patients), which is not on this map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06496711 narecruitingnot on this map

IMPLEMENT - Model Project for the Cross-sector Implementation of a Comprehensive and Quality-assured Sports and Exercise Therapy for Cancer Patients

TypeinterventionalSponsorUniversity of CologneRan2023 to 2026Enrolled600ConditionsCancerArmsCancer Patients, Institutions and their employees in the treatment and/or counseling of cancer patients
3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. A qualitative analysis of cancer patients' views on facilitators and barriers for the implementation of oncological exercise therapy.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

33 authors.

Mirko Brandes *Leibniz-Institute for Prevention Research and Epidemiology - BIPS, Bremen, Germany.
Anika Berling-Ernst *Department I of Internal Medicine, Center of Integrated Oncology Aachen Bonn Cologne Duesseldorf, University Hospital of Cologne, Cologne, Germany. anika.berling-ernst@uk-koeln.de.
Hansjoerg BaurechtDepartment of Epidemiology and Preventive Medicine, University of Regensburg, University Hospital Regensburg, Regensburg, Germany.
Wiebke JensenDepartment of Oncology, BMT with Section Pneumology, Hubertus Wald Tumor Center - University Cancer Center Hamburg, University Medical Center Hamburg-Eppendorf, Hematology, Germany.
Miriam GötteWest German Cancer Center, University Hospital Essen, Essen, Germany.
Anne HerrmannDepartment of Epidemiology and Preventive Medicine, Medical Sociology, University of Regensburg, Regensburg, Germany.
Daniela FuhrLeibniz-Institute for Prevention Research and Epidemiology - BIPS, Bremen, Germany.
Heike SchmidtMedical Faculty of Martin, University Clinic and Outpatient Clinic for Radiotherapy, Luther University Halle-Wittenberg, Halle, Germany.
Antonia LucasUniversity Cancer Center Schleswig-Holstein, University Hospital Schleswig-Holstein, Kiel, Germany.
Bernardine MadlSchool of Medicine and Health, Department for Preventive Sports Medicine and Sports Cardiology, Technical University of Munich, TUM University Hospital, Munich, Germany.
Simon ElmersDepartment of Oncology, BMT with Section Pneumology, Hubertus Wald Tumor Center - University Cancer Center Hamburg, University Medical Center Hamburg-Eppendorf, Hematology, Germany.
Thorsten SchmidtUniversity Cancer Center Schleswig-Holstein, University Hospital Schleswig-Holstein, Kiel, Germany.
Christine WelkerDepartment of Epidemiology and Preventive Medicine, University of Regensburg, University Hospital Regensburg, Regensburg, Germany.
Andre GollaHealth Service Research Working Group| Acute Care, Medical Faculty of Martin Luther, University Medicine Halle (Saale), University Halle-Wittenberg, Halle, Germany.
Annalena WehnerDepartment of Medicine III and Comprehensive Cancer Center (CCC Munich LMU), LMU University Hospital Munich, Munich, Germany.
Dominik MorlokDepartment of Epidemiology and Preventive Medicine, Medical Sociology, University of Regensburg, Regensburg, Germany.
Jana RueterDepartment of Epidemiology and Preventive Medicine, Medical Sociology, University of Regensburg, Regensburg, Germany.
Janina MeuerLeibniz-Institute for Prevention Research and Epidemiology - BIPS, Bremen, Germany.
Melanie ReitzDepartment I of Internal Medicine, Center of Integrated Oncology Aachen Bonn Cologne Duesseldorf, University Hospital of Cologne, Cologne, Germany.
Jane KerstenDepartment I of Internal Medicine, Center of Integrated Oncology Aachen Bonn Cologne Duesseldorf, University Hospital of Cologne, Cologne, Germany.
Rebecca ZimmerDepartment of Pediatric Hematology/Oncology, Pediatrics III, West German Cancer Center, University Hospital Essen, Essen, Germany.
Yvonne GadczikowskeLeibniz-Institute for Prevention Research and Epidemiology - BIPS, Bremen, Germany.
Renee StarkProfessorship of Public Health and Prevention, School of Medicine and Health, Technical University of Munich, Munich, Germany.
Kathrin HegenbergProfessorship of Public Health and Prevention, School of Medicine and Health, Technical University of Munich, Munich, Germany.
Michael LaxyProfessorship of Public Health and Prevention, School of Medicine and Health, Technical University of Munich, Munich, Germany.
Martin HalleSchool of Medicine and Health, Department for Preventive Sports Medicine and Sports Cardiology, Technical University of Munich, TUM University Hospital, Munich, Germany.
Patrick JahnHealth Service Research Working Group| Acute Care, Medical Faculty of Martin Luther, University Medicine Halle (Saale), University Halle-Wittenberg, Halle, Germany.
Carsten BokemeyerDepartment of Oncology, BMT with Section Pneumology, Hubertus Wald Tumor Center - University Cancer Center Hamburg, University Medical Center Hamburg-Eppendorf, Hematology, Germany.
Sebastian TheurichDepartment of Medicine III and Comprehensive Cancer Center (CCC Munich LMU), LMU University Hospital Munich, Munich, Germany.
Hajo ZeebLeibniz-Institute for Prevention Research and Epidemiology - BIPS, Bremen, Germany.
Michael LeitzmannDepartment of Epidemiology and Preventive Medicine, University of Regensburg, University Hospital Regensburg, Regensburg, Germany.
Freerk T BaumannDepartment I of Internal Medicine, Center of Integrated Oncology Aachen Bonn Cologne Duesseldorf, University Hospital of Cologne, Cologne, Germany.
IMPLEMENT consortium

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAlthough quality-assured oncological exercise therapy (qOET) has proven effective for cancer patients at any stage of treatment and during aftercare, it is not yet incorporated into standard care in Germany and, to the best of our knowledge, in any other country. A collaboration involving eight German research institutions was initiated to investigate the barriers and facilitators to implementation and promote the wider dissemination of qOET for cancer patients across various settings in Germany.

methodsThe IMPLEMENT project is designed as an exploratory study with a quasi-experimental design and a mixed-methods approach, combining qualitative and quantitative data collection. Institutions involved in the treatment and/or aftercare of cancer patients will be approached to identify key barriers and facilitators of qOET. Based on these findings, a set of implementation strategies (IPS) will be developed, implemented, and evaluated to facilitate the delivery of qOET for cancer patients. We aim to develop a variety of IPS for different contexts: urban settings (e.g. qualifying local aftercare institutions to provide qOET); rural settings (e.g. a hybrid approach for areas with limited access to local qOET services); adult cancer patients (e.g. focussing on patient education); and children and young cancer patients (e.g. offering consultations with training therapy experts). Additionally, interface management, training concepts, digital support, and economic evaluation will be considered to further promote the wider dissemination of qOET. The impact of the IPS will primarily be measured by the reach of qOET, assessed by comparing the number of cancer patients receiving qOET before and after implementation. DISCUSSION: The aim of IMPLEMENT is to address key barriers and facilitators for the implementation of qOET in Germany, and to increase the number of cancer patients receiving qOET in the long term. Following the project, successful IPS will be disseminated for broader application. The IMPLEMENT consortium aims to make a significant contribution to the long-term integration of qOET into the standard care of cancer patients in Germany and prospectively for other countries as well.

trial registrationClin. TRIALS: NCT06496711. German Clinical Trial Register (Deutsches Register Klinischer Studien - DRKS): 00032292. Bavarian Cancer Research Center (Bayerisches Krebsforschungszentrum (BZKF bzw. ZKS): DZ-2024-2165-9.

Indexed as

Exercise TherapyNeoplasmsQuality Assurance, Health CareGermanyHumansMedical OncologyNon-Randomized Controlled Trials as TopicCancerImplementationOncological exercise therapyStrategies

Identifiers

PMID40241071
PMCPMC12004655

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.