Evidence map›Paper›PMID 40241063›Full record

ArticleBMC musculoskeletal disorders2025

A comparative study on clinical outcomes and safety of accurate anterior cervical ossified posterior longitudinal ligament en bloc resection versus piecemeal resection in patients with ossification of the cervical posterior longitudinal ligament: a propensity score-matching analysis.

Kefu Chen, Hao Zhang, Yiwei Lu, Jian Zhang, Xiaodong Liu, Lianshun Jia, Xingcheng Dong, Xiongsheng Chen

Abstract readComparative Study
In one paragraph

Article in BMC musculoskeletal disorders, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

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2citing papers in PubMed
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3 · Its place in the literature

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2 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Kefu Chen *Shanghai Changhai Hospital, Shanghai, China.
Hao Zhang *Naval Medical Center of Chinese People's Liberation Army, Shanghai, China.
Yiwei Lu *Shanghai Changzheng Hospital, Shanghai, China.
Jian ZhangJining First People's Hospital, Jining, China.
Xiaodong LiuJing'an District Zhabei Central Hospital, Shanghai, China.
Lianshun JiaShanghai Changzheng Hospital, Shanghai, China.
Xingcheng DongThe Fourth Affiliated Hospital, Soochow University, Suzhou, China. dxcorthopedics@163.com.
Xiongsheng ChenShanghai First People's Hospital, Shanghai, China. cxsorthopedics@163.com.

Funding

National Natural Science Foundation of China 82172472
6 · The paper itself

Abstract

objectiveThe anterior approach for cervical ossification of posterior longitudinal ligament (OPLL) excision can improve long-term neurofunctional recovery by providing direct spinal cord decompression. The objective of the present study was to compare the clinical outcomes and complications between accurate anterior cervical ossified posterior longitudinal ligament en bloc resection (ACOE) versus piecemeal resection (ACOP) using propensity score-matching analysis.

methodsIncluded in this study were 189 OPLL patients (65 female) who underwent anterior cervical surgery, with a mean age of 54.85 years. Of them, 105 patients (39 female) with a mean age of 55.69 years underwent ACOE, and the remaining 84 patients (26 female) with a mean age of 53.80 underwent ACOP. Of the 189 patients, 70 patients (37%) had a canal occupying ratio (COR) ≥ 50%, and therefore the patient data were stratified by COR with 50%. The clinical outcomes were compared between the two groups during a at least 27-month follow-up period.

resultsThe mean final follow-up JOA score in ACOE group was higher than that in ACOP group. The JOA recovery rate of patients with COR ≥ 50% was higher in ACOE group. The mean operative time and intraoperative blood loss were both lower in ACOE group. However, postoperative complications were not significantly different between the two groups.

conclusionThis study demonstrated that the ACOE technique gained higher JOA recovery rates and better neurological recovery than ACOP for OPLL patients with COR ≥ 50%. In addition, ACOE offered a shorter operative time and less intraoperative blood loss as compared with ACOP. Therefore, the postoperative complications were not more common between two groups.

Indexed as

Cervical VertebraeDecompression, SurgicalOssification of Posterior Longitudinal LigamentAdultAgedFemaleFollow-Up StudiesHumansMaleMiddle AgedPostoperative ComplicationsPropensity ScoreRetrospective StudiesTreatment OutcomeCanal occupying ratioNeurologic recoveryOssification of posterior longitudinal ligamentSpinal CanalTreatment outcome

Identifiers

PMID40241063
PMCPMC12004819

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.