Evidence map›Paper›PMID 40241024›Full record

ArticleBMC medical imaging2025

Low-dose and low-contrast computed tomography pulmonary angiography in pediatric with pulmonary embolism: a prospective study.

Kaihua Yang, Jihang Sun, Yidi Zhao, Xin Yang, Lifang Sun, Ling Wu, Yue Liu, Shengli Shi

Abstract read
In one paragraph

Article in BMC medical imaging, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
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  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Kaihua Yang *Medical Imaging Department, Children's Hospital Affiliated to Zhengzhou University, Zhengzhou, Henan, 450018, China.
Jihang Sun *Imaging Center, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, Beijing, 100045, China.
Yidi ZhaoMedical Imaging Department, Children's Hospital Affiliated to Zhengzhou University, Zhengzhou, Henan, 450018, China.
Xin YangMedical Imaging Department, Children's Hospital Affiliated to Zhengzhou University, Zhengzhou, Henan, 450018, China.
Lifang SunMedical Imaging Department, Children's Hospital Affiliated to Zhengzhou University, Zhengzhou, Henan, 450018, China.
Ling WuMedical Imaging Department, Children's Hospital Affiliated to Zhengzhou University, Zhengzhou, Henan, 450018, China.
Yue LiuImaging Center, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, Beijing, 100045, China. liuyue20136@163.com.
Shengli ShiMedical Imaging Department, Children's Hospital Affiliated to Zhengzhou University, Zhengzhou, Henan, 450018, China. s0220ssl@hotmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveWe evaluated the feasibility of reducing contrast agent and radiation dose in pediatric computed tomography pulmonary angiography (CTPA) while ensuring image quality. MATERIALS AND

methodsIn this prospective study, two readers assessed the computed tomography (CT) image quality (using a 5-point scale (1: undiagnosable and 5: excellent) and objective evaluation criteria (measuring CT and noise values of the left atrium and pulmonary trunk) of 116 patients who underwent pulmonary artery computed tomography angiography (CTA) from January 2023 to April 2024. independent sample t-test and Chi-square test were used to analyze and evaluate group differences.

resultFifty-eight participants were enrolled in the study group (mean age, 6.86 years ± 2.74, 30 males) and fifty-eight participants were enrolled in the control group (mean age, 6.71 years ± 2.59, 22 males). The radiation dose was significantly decreased in the study group (study group, 3.01 ± 0.24 mGy, control group 3.77 ± 1.06 mGy, p < 0.001). Overall quality was higher in control group, but displaying ability of pulmonary artery trunk and branch was higher in study group (p < 0.001).

conclusionThis study proved that a low-dose, low-contrast CTPA strategy could reduce radiation dosage by 50% and contrast agent by 20% while maintaining a satisfying image quality.

Indexed as

Computed Tomography AngiographyContrast MediaPulmonary ArteryPulmonary EmbolismRadiation DosageAdolescentChildChild, PreschoolFeasibility StudiesFemaleHumansMaleProspective StudiesContrast MediaChildrenComputed tomography pulmonary angiographyLow-contrastLow-dosePulmonary embolism

Identifiers

PMID40241024
PMCPMC12004619

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.