Evidence map›Paper›PMID 40240946›Full record

ArticleJournal of the American Heart Association2025

Global Burden of Cardiovascular Disease Attributable to Sugar-Sweetened Beverages in Middle-Aged Adults: An Age-Period-Cohort Modelling Study.

Xiao Liu, Jie Bai, Xinrui Qi, Yifan Wu, Jitao Ling, Xinyu Liu, Tiangang Song, Jing Zhang, Zhiwei Yan, Deju Zhang and 1 more

Abstract read
In one paragraph

Article in Journal of the American Heart Association, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Xiao LiuDepartment of Endocrinology Medicine, the Second Affiliated Hospital, Jiangxi Medical College Nanchang University Nanchang Jiangxi China.ORCID 0000-0001-8252-3435
Jie BaiDepartment of Endocrinology Medicine, the Second Affiliated Hospital, Jiangxi Medical College Nanchang University Nanchang Jiangxi China.
Xinrui QiDepartment of Endocrinology Medicine, the Second Affiliated Hospital, Jiangxi Medical College Nanchang University Nanchang Jiangxi China.ORCID 0009-0007-8766-9119
Yifan WuDepartment of Endocrinology Medicine, the Second Affiliated Hospital, Jiangxi Medical College Nanchang University Nanchang Jiangxi China.
Jitao LingDepartment of Endocrinology Medicine, the Second Affiliated Hospital, Jiangxi Medical College Nanchang University Nanchang Jiangxi China.
Xinyu LiuDepartment of Biochemistry and Molecular Biology Johns Hopkins Bloomberg School of Public Health Baltimore MD USA.
Tiangang SongDepartment of Endocrinology Medicine, the Second Affiliated Hospital, Jiangxi Medical College Nanchang University Nanchang Jiangxi China.
Jing ZhangDepartment of Anesthesiology, the Second Affiliated Hospital, Jiangxi Medical College Nanchang University Nanchang Jiangxi China.
Zhiwei YanDepartment of Sports Rehabilitation, College of Kinesiology Shenyang Sport University Shenyang Liaoning China.ORCID 0000-0002-1754-9126
Deju ZhangFood and Nutritional Sciences, School of Biological Sciences The University of Hong Kong Hong Kong China.ORCID 0000-0001-5671-3227
Peng YuDepartment of Endocrinology Medicine, the Second Affiliated Hospital, Jiangxi Medical College Nanchang University Nanchang Jiangxi China.ORCID 0000-0002-9405-7686

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCardiovascular disease (CVD) presents a significant burden among middle-aged adults (aged 35-64). Diet high in sugar-sweetened beverages is a notable CVD risk factor.

methodsUsing Global Burden of Disease data from 1990 to 2019, age-standardized rates (ASRs) and average annual percentage change of ASRs were used to describe this burden and its changing trend.

resultsIn 2019, global CVD-related ASR (per 100 000) of deaths attributable to sugar-sweetened beverages in middle-aged adults reached 1.91 (95% uncertainty interval [UI], 1.07-2.63) compared with 2.75 (95% UI, 1.76-3.59) in 1990. The global ASR of disability-adjusted life years (DALYs) reached 69.71 in 2019 (95% UI, 38.38-96.36) compared with 97.98 (95% UI, 62.29-128.39) in 1990. Men had more than twice the deaths and DALYs as women. Low and low-middle sociodemographic index regions exhibited a higher burden of DALYs and deaths. In 2019, India and China had the highest numbers of deaths and DALYs and the Solomon Islands and Afghanistan recorded the highest ASRs of deaths and DALYs. A negative linear correlation was observed between sociodemographic index and ASRs of deaths (

conclusionsGlobally, sugar-sweetened beverages have contributed to a substantial increase in DALYs and deaths related to CVD in middle-aged adults over the past 30 years, especially among men and in low sociodemographic index countries.

Indexed as

Cardiovascular DiseasesSugar-Sweetened BeveragesAdultAge FactorsDisability-Adjusted Life YearsFemaleGlobal Burden of DiseaseGlobal HealthHumansMaleMiddle AgedRisk AssessmentRisk Factorscardiovascular diseasedeathsdisability‐adjusted life yearsglobal burden of diseasemiddle‐aged adultssugar‐sweetened beverages

Identifiers

PMID40240946
PMCPMC12184267

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.