ArticleNature2025
Bovine H5N1 binds poorly to human-type sialic acid receptors.
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In one paragraph
Article in Nature, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
25 citing papers in PubMed.
- Beyond H5N1: influenza A virus infection in bovine udder organoids.Emerging microbes & infections · 2026Article
- In silico analysis of pH stabilising mutations of hemagglutinin of influenza A virus H5N1 clade 2.3.4.4b.Npj viruses · 2026Review
- Acquisition of specific human respiratory tract binding by 2.3.4.4b H5N1 hemagglutinins requires multiple mutations.Journal of virology · 2026Article
- Standing HA phenotypic breadth shapes H5N1 cross-host potential.Research square · 2026Article
- Clade 2.3.4.4b H5N1 influenza virus and SARS-CoV-2 seroprevalence among owned and feral cats in Philadelphia and surrounding communities.bioRxiv : the preprint server for biology · 2026Article
- Hemagglutinin double-mutation enhances binding of human-infecting avian influenza virus clade 2.3.4.4b H5Ny to human and SLeEMBO reports · 2026Article
- Quantitative Microbial Risk Assessment of Human H5N1 Infection From Consumption of Fluid Cow's Milk.Risk analysis : an official publication of the Society for Risk Analysis · 2026Article
- An overview of HPAI H5N1 clade 2.3.4.4b and its emerging threat in mainland Australia: Identified knowledge gaps.One health (Amsterdam, Netherlands) · 2026Review
- Hemagglutinin E190D substitution in clade 2.3.4.4b A(H5N1) influenza virus reduces receptor binding and viral fitness.Npj viruses · 2026Article
- Cross-reactive human antibody responses to H5N1 influenza virus neuraminidase are shaped by immune history.Nature communications · 2026Article
- Tropism and Replication Competence of Cattle Influenza A(H5N1) Genotype B3.13 Virus in Human Bronchus and Lung Tissue.Emerging infectious diseases · 2026Article
- Spatial localization of avian and human influenza A virus receptors in male and female bovine reproductive tissues.Scientific reports · 2026Article
- Polymerase mutations underlie early adaptation of H5N1 influenza virus to dairy cattle and other mammals.Nature communications · 2026Article
- Influenza A Virus H5N1 Subtype: Resurgent Interspecies and Intercontinental Transmission, and a New Host.Pathogens (Basel, Switzerland) · 2025Review
- The potential of H5N1 viruses to adapt to bovine cells varies throughout evolution.Nature communications · 2025Article
- Immunological and virological questions for H5N1 pandemic emergence.ImmunoHorizons · 2025Review
- Highly pathogenic avian H5N1 influenza A virus replication in ex vivo cultures of bovine mammary gland and teat tissues.Emerging microbes & infections · 2025Article
- The hemagglutinin proteins of clades 1 and 2.3.4.4b H5N1 highly pathogenic avian influenza viruses exhibit comparable attachment patterns to avian and mammalian tissues.Journal of virology · 2025Article
- Chemoenzymatic Synthesis of Asymmetric Bisecting Bi-, Tri-, and Tetra-AntennaryJournal of the American Chemical Society · 2025Article
- Cross-reactive human antibody responses to H5N1 influenza virus neuraminidase are shaped by immune history.medRxiv : the preprint server for health sciences · 2025Article
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Authors and funding
12 authors.
Jefferson J S Santos *Department of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.ORCID http://orcid.org/0000-0001-5895-4163
Shengyang Wang *Department of Molecular Medicine and Department of Immunology and Microbiology, Scripps Research Institute, La Jolla, CA, USA.
Ryan McBride *Department of Molecular Medicine and Department of Immunology and Microbiology, Scripps Research Institute, La Jolla, CA, USA.
Lorin Adams *Worldwide Influenza Centre, The Francis Crick Institute, London, UK.ORCID http://orcid.org/0000-0001-8357-2327
Ruth HarveyWorldwide Influenza Centre, The Francis Crick Institute, London, UK.
Yan ZhaoDepartment of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.
Antoni G WrobelStructural Biology of Disease Processes Lab, Francis Crick Institute, London, UK.ORCID http://orcid.org/0000-0002-6680-5587
Steven GamblinStructural Biology of Disease Processes Lab, Francis Crick Institute, London, UK.ORCID http://orcid.org/0000-0001-5331-639X
John SkehelStructural Biology of Disease Processes Lab, Francis Crick Institute, London, UK.
Nicola S LewisWorldwide Influenza Centre, The Francis Crick Institute, London, UK. nicola.lewis@crick.ac.uk.ORCID http://orcid.org/0000-0001-9496-4756
James C PaulsonDepartment of Molecular Medicine and Department of Immunology and Microbiology, Scripps Research Institute, La Jolla, CA, USA. jpaulson@scripps.edu.ORCID http://orcid.org/0000-0003-4589-5322
Scott E HensleyDepartment of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA. hensley@pennmedicine.upenn.edu.ORCID http://orcid.org/0000-0002-2928-7506
Funding
No grant is acknowledged in the PubMed record.
Abstract
PubMed holds no abstract for this paper.
Identifiers
PMID
40240859What OpenQuestion holds
Textmetadata
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.