Evidence map›Paper›PMID 40240769›Full record

ArticleSchizophrenia (Heidelberg, Germany)2025

Psychiatric factors predict type 2 diabetes mellitus in US Veterans.

Lora Lee Pless, Chantele Mitchell-Miland, Yeon-Jung Seo, Charles B Bennett, Zachary Freyberg, Gretchen L Haas

Abstract read
In one paragraph

Article in Schizophrenia (Heidelberg, Germany), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Lora Lee PlessVISN 4 Mental Illness Research Education and Clinical Center (MIRECC), VA Pittsburgh Healthcare System, Pittsburgh, PA, USA. lora.pless@pitt.edu.ORCID http://orcid.org/0000-0003-0163-3689
Chantele Mitchell-MilandVISN 4 Mental Illness Research Education and Clinical Center (MIRECC), VA Pittsburgh Healthcare System, Pittsburgh, PA, USA.
Yeon-Jung SeoVISN 4 Mental Illness Research Education and Clinical Center (MIRECC), VA Pittsburgh Healthcare System, Pittsburgh, PA, USA.
Charles B BennettVISN 4 Mental Illness Research Education and Clinical Center (MIRECC), VA Pittsburgh Healthcare System, Pittsburgh, PA, USA.
Zachary FreybergVISN 4 Mental Illness Research Education and Clinical Center (MIRECC), VA Pittsburgh Healthcare System, Pittsburgh, PA, USA.ORCID http://orcid.org/0000-0001-6460-0118
Gretchen L HaasVISN 4 Mental Illness Research Education and Clinical Center (MIRECC), VA Pittsburgh Healthcare System, Pittsburgh, PA, USA. gretchen.haas@va.gov.ORCID http://orcid.org/0000-0002-3413-9196

Funding

Genetics Association in Schizophrenia and Other DisordersR37MH057881 · NIMH · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI DEVLIN, BERNIE · 2013 to 2022
$5.4M
Novel dopaminergic mechanisms of islet hormone secretion and antipsychotic drug-induced metabolic disturbancesR01DK124219 · NIDDK · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI FREYBERG, ZACHARY · 2021 to 2023
$1.2M
NIDDK NIH HHS R01 DK124219NIMH NIH HHS R37 MH057881U.S. Department of Defense (United States Department of Defense) PR210207U.S. Department of Health & Human Services | National Institutes of Health (NIH) R01DK124219U.S. Department of Health & Human Services | National Institutes of Health (NIH) R37MH057881
6 · The paper itself

Abstract

Co-occurrence of type 2 diabetes mellitus (T2D) and serious mental illnesses (SMI) is prevalent yet underappreciated, and significantly contributes to increased morbidity and reduced lifespan. There is, therefore, a need to identify T2D risk factors to inform preventative approaches to the care of SMI-diagnosed patients. Our objective was to use predictive modeling methods to capture risk factors for T2D in a sample of 618,203 Veterans using data obtained from hospital electronic health records (EHR). This case-control study assessed VISN4 Veterans with and without T2D diagnoses and SMI diagnoses (schizophrenia, SZ; schizoaffective, SZA; bipolar disorder, BD; major depression, MDD; 2009-2019). Demographic variables and medications were obtained from the EHR. Following rigorous data quality control, 543,979 Veterans qualified for analysis (Age

Identifiers

PMID40240769
PMCPMC12003899

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.