Evidence map›Paper›PMID 40240744›Full record

ReviewJournal of religion and health2025

Theological and Ethical Perspectives on Gene Editing and the Sanctity of Life: Rare Genetic Diseases in the Philippines as a Model.

Mary Anne D Chiong, Allan A Basas

Abstract readReview
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In one paragraph

Review in Journal of religion and health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Mary Anne D ChiongDepartment of Biochemistry, Molecular Biology and Nutrition, Faculty of Medicine and Surgery, University of Santo Tomas, Manila, Philippines. mdchiong@ust.edu.ph.ORCID http://orcid.org/0000-0002-1928-3608
Allan A BasasInstitute of Religion, University of Santo Tomas, Manila, Philippines.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This paper examines the interplay between the sacredness of life and gene editing in the context of rare genetic diseases. Rare genetic disorders caused by gene mutations often come with limited treatment options. Gene editing techniques present a promising solution by targeting and repairing defective genes. The discussion begins with an overview of the science behind gene editing and its potential applications in treating rare diseases, highlighting three specific genetic conditions affecting Filipinos. It then explores the ethical and theological dimensions of gene editing, emphasizing the Imago Dei doctrine, which underscores human dignity and moral responsibility as well as ethical principles in light of Christian virtues. A comparative analysis between therapeutic somatic gene editing and germline editing is highlighted in the discussions. Using the See-Judge-Act framework, the paper examines the potential of gene editing through the lens of Catholic Church's teachings on human dignity and offers practical insights for applying the theological and ethical considerations in addressing the therapeutic options for rare genetic diseases righteously.

Indexed as

Gene EditingGenetic Diseases, InbornRare DiseasesReligion and MedicineCatholicismGenetic TherapyHumansPhilippinesGermline gene editingHuman dignityImago DeiRare genetic diseasesSomatic gene editing

Identifiers

PMID40240744

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.