Evidence map›Paper›PMID 40240717›Full record

ArticleArchives of virology2025

Longitudinal molecular epidemiology of human adenovirus in pediatric respiratory infections: a 12-year study in Korea (2008-2019).

Bin Ahn, Ki Wook Yun, Hoan Jong Lee, Sun Jung Kim, Seong Yeon Lee, Eun Hwa Choi

Abstract read
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In one paragraph

Article in Archives of virology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Bin AhnDepartment of Pediatrics, Seoul National University College of Medicine, 101 Daehak-ro, Jongno-gu, Seoul, 03080, Korea.ORCID https://orcid.org/0000-0002-3806-4275
Ki Wook YunDepartment of Pediatrics, Seoul National University College of Medicine, 101 Daehak-ro, Jongno-gu, Seoul, 03080, Korea.ORCID https://orcid.org/0000-0002-0798-6779
Hoan Jong LeeDepartment of Pediatrics, Seoul National University College of Medicine, 101 Daehak-ro, Jongno-gu, Seoul, 03080, Korea.ORCID https://orcid.org/0000-0001-9643-3692
Sun Jung KimDepartment of Pediatrics, Seoul National University Children's Hospital, Seoul, Korea.ORCID https://orcid.org/0000-0002-4668-3690
Seong Yeon LeeDepartment of Pediatrics, Seoul National University Children's Hospital, Seoul, Korea.ORCID https://orcid.org/0000-0002-0800-8125
Eun Hwa ChoiDepartment of Pediatrics, Seoul National University College of Medicine, 101 Daehak-ro, Jongno-gu, Seoul, 03080, Korea. eunchoi@snu.ac.kr.ORCID http://orcid.org/0000-0002-5857-0749

Funding

Ministry of Education 2022R1F1A1073624
6 · The paper itself

Abstract

Human adenovirus (HAdV) is a leading cause of respiratory infections, with clinical manifestations and disease severity varying by type. In this study, we analyzed HAdV types in South Korea over a 12-year period before the COVID-19 pandemic. From January 2008 to December 2019, HAdV isolates were prospectively collected from children with suspected respiratory infections at a single tertiary center. HAdV typing was performed through sequence analysis of hexon gene hypervariable regions (HVRs) 1-6. Among 350 HAdV isolates, members of four species (A, B, C, and E) and 10 types (1-6, 31, 34, 35, and 55) were identified. Overall, HAdV-3 was most prevalent (49.4%), followed by HAdV-2 (19.1%), HAdV-1 (14.6%), and HAdV-4 (6.6%). HAdV-3 caused four recurrent outbreaks at intervals of 3 to 4 years without significant genetic changes in the hexon HVRs. HAdV species C (types 1, 2, 5, and 6) was detected endemically throughout the study period. Notably, HAdV-55, which was associated with fatal cases in military recruits in South Korea during 2017-2018, appeared in pediatric cases. HAdV epidemiology studies are important for providing clinical data on circulating HAdVs in children, and there is a need for ongoing surveillance and research.

Indexed as

Adenoviruses, HumanAdenovirus Infections, HumanRespiratory Tract InfectionsAdolescentCapsid ProteinsChildChild, PreschoolFemaleHumansInfantLongitudinal StudiesMaleMolecular EpidemiologyPhylogenyProspective StudiesRepublic of KoreaCapsid Proteins

Identifiers

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.