Trial reportLasers in medical science2025
Comparison of the effects of antibiotic therapy and photobiomodulation with red and infrared lasers on the healing of postextraction sockets of third molars: A randomised controlled trial.
Trial report in Lasers in medical science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
4 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Effects of Near Infrared Light on Surgical Wound Healing: A Systematic Review and Meta-Analysis.International wound journal · 2026Pooled it
- Effects of Dual Wavelength Photobiomodulation on Osseointegration in Grafted Areas.Lasers in surgery and medicine · 2026Article
- Photobiomodulation Therapy (PBMT) with Dual-Wavelength Enhances Reduction of Inflammation After Third Molar Extraction Compared with Red Laser PBMT: A Randomized Clinical Trial.Journal of clinical medicine · 2026Article
- The Effect of Antimicrobial Photodynamic Therapy on the Healing of the Post-Extraction Socket of the Mandibular Third Molar: A Randomized Clinical Study.Journal of clinical medicine · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
The aim of this study was to evaluate the effects of dual-wavelength photobiomodulation (PBMT) compared with antibiotic therapy with amoxicillin on postoperatory healing and symptoms after third molar extraction. Sixty patients were randomly allocated in a parallel model according to the adjunctive therapy applied after extraction of all 4 third molars in one single session (n = 15): CTR: no adjunctive therapy; ATB3: amoxicillin for 3 days; ATB7: amoxicillin for 7 days; PBMT: PBMT at dual wavelengths (λ 660 nm and λ 808 nm, 200 mW). Clinical analyses (assessment of oedema, mouth opening variation, and soft tissue healing) and patient-centred analyses (application of a visual analogue scale (VAS) to assess pain, inflammation, bleeding, difficulty during opening the mouth, and chewing) were performed at 3, 7, 14, 30, and 90 days after the surgical procedure. Radiographic analysis was performed to evaluate bone repair by observing the radiographic density and fractal dimension immediately and 90 days after tooth extraction. PBMT reduced the loss of mouth opening amplitude and the sensation of pain and oedema. There were no differences between the ATB and CTR groups. PBMT has a beneficial effect on postoperative control (reduction in inflammation and pain) after third molar extraction, and ATB does not have a beneficial effect on postoperative control after these surgeries. PBMT reduces morbidity after third molar extraction, whereas antibiotic therapy has no beneficial effect. Trial registration Brazilian Registry of Clinical Trials (REBEC-RBR- 4bct2 km-Date of registration: 12/06/2021) under number U1111 - 1263-9675.
Indexed as
Identifiers
40240714What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.