Evidence map›Paper›PMID 40240537›Full record

ReviewCalcified tissue international2025

Grading Pseudofractures-The "Breach-Beak-Bump-Bridge" Approach.

Lothar Seefried, Dominik Rak, Franca Genest

Abstract readReview
In one paragraph

Review in Calcified tissue international, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Grading Pseudo Fractures.Calcified tissue international · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Lothar SeefriedDepartment of Osteology and Clinical Trial Unit, Orthopedic Hospital, König-Ludwig Haus, Julius-Maximilians-Universität Würzburg, Brettreichstraße 11, 97074, Würzburg, Bavaria, Germany. lothar.seefried@uni-wuerzburg.de.ORCID 0000-0003-1154-3388
Dominik RakDepartment of Osteology and Clinical Trial Unit, Orthopedic Hospital, König-Ludwig Haus, Julius-Maximilians-Universität Würzburg, Brettreichstraße 11, 97074, Würzburg, Bavaria, Germany.ORCID 0000-0003-3118-6525
Franca GenestDepartment of Osteology and Clinical Trial Unit, Orthopedic Hospital, König-Ludwig Haus, Julius-Maximilians-Universität Würzburg, Brettreichstraße 11, 97074, Würzburg, Bavaria, Germany.ORCID 0000-0001-6233-4805

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pseudofractures are atraumatic radiolucencies resulting from compromised bone mineralization and are often associated with poor clinical outcomes in patients with skeletal disorders. The incidence, clinical course of healing, and the risk of recurrence of pseudofractures are not well characterized, not least because pseudofractures and fractures are regularly reported under the general term "fractures," despite underlying pathophysiological differences. Accordingly, this report is intended to conceptualize a grading scale for identifying and assessing pseudofractures. The scale was developed based on our clinical experience with. The proposed taxonomy includes 4 radiographically distinct stages, progressing from an unreactive initial Breach (Stage 1) to a stage with a visible Beak (Stage 2), appearance of a rounded Bump (Stage 3), and formation of a Bridge (Stage 4) across the interline. These scores correspond to radiographic transformations observed along the course of pseudofracture consolidation, although these stages of healing are reversible, and stagnation or relapse may occur at any stage. Dislocation should be indicated by adding a "d" to the score; adding an "s" indicates that the bone is clinically stable, meaning pain-free full weight-bearing is possible, because of surgical stabilization or sustainable cortical bridging (typically in Stage 4 or 0 [consolidation]). The scale may be used for any pseudofracture regardless of anatomical site or etiology. The proposed Breach-Beak-Bump-Bridge (4B) concept is a tool that can be used in clinical practice to assess pseudofractures over time and to improve specificity and clarity in communication of these findings.

Indexed as

Fractures, BoneFracture HealingHumansRadiography4B scaleHypophosphatasiaOsteomalaciaPseudofracture

Identifiers

PMID40240537
PMCPMC12003480

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.