Evidence map›Paper›PMID 40240485›Full record

ArticleCell research2025

Pyrimidine synthase CAD deamidates and inactivates p53.

Yue Qi, Zizheng Tan, Hanyu Chen, Ziqi Xiao, Liang Zhang, Boxuan Wu, Chennan Liu, Yunqian Gao, Xueyan Yang, Lingqian Wu and 2 more

Abstract readLetter
In one paragraph

Article in Cell research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Yue Qi *Obstetrics and Gynecology Hospital, State Key Laboratory of Genetic Engineering, School of Life Sciences, Children's Hospital, Fudan University, Shanghai, China.
Zizheng Tan *Shanghai Key Laboratory of Metabolic Remodeling and Health, Institute of Metabolism and Integrative Biology, Fudan University, Shanghai, China.
Hanyu ChenObstetrics and Gynecology Hospital, State Key Laboratory of Genetic Engineering, School of Life Sciences, Children's Hospital, Fudan University, Shanghai, China.
Ziqi XiaoShanghai Key Laboratory of Metabolic Remodeling and Health, Institute of Metabolism and Integrative Biology, Fudan University, Shanghai, China.
Liang ZhangObstetrics and Gynecology Hospital, State Key Laboratory of Genetic Engineering, School of Life Sciences, Children's Hospital, Fudan University, Shanghai, China.
Boxuan WuShanghai Key Laboratory of Metabolic Remodeling and Health, Institute of Metabolism and Integrative Biology, Fudan University, Shanghai, China.
Chennan LiuShanghai Key Laboratory of Metabolic Remodeling and Health, Institute of Metabolism and Integrative Biology, Fudan University, Shanghai, China.
Yunqian GaoPediatric Translational Medicine Institute, Shanghai Children's Medical Center, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.
Xueyan YangObstetrics and Gynecology Hospital, State Key Laboratory of Genetic Engineering, School of Life Sciences, Children's Hospital, Fudan University, Shanghai, China.
Lingqian WuThe Center for Medical Genetics, Hunan Key Laboratory of Medical Genetics & Hunan Key Laboratory of Animal Models for Human Diseases, School of Life Sciences, Central South University, Changsha, Hunan, China.
Lei LuShanghai Key Laboratory of Metabolic Remodeling and Health, Institute of Metabolism and Integrative Biology, Fudan University, Shanghai, China. lulei@fudan.edu.cn.
Hongyan WangObstetrics and Gynecology Hospital, State Key Laboratory of Genetic Engineering, School of Life Sciences, Children's Hospital, Fudan University, Shanghai, China. wanghy@fudan.edu.cn.

Funding

National Natural Science Foundation of China (National Science Foundation of China) 82150008National Natural Science Foundation of China (National Science Foundation of China) 82471733Science and Technology Commission of Shanghai Municipality (Shanghai Municipal Science and Technology Commission) 20JC1418500
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID40240485
PMCPMC12205080

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.