ArticleScientific reports2025
Chiral carbon dot as a fluorescent stain with enantiomer-dependent cell imaging.
Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
2 citing papers in PubMed.
- A simple design of carbon dots for dual-mode pH sensing and monitoring food freshness.Mikrochimica acta · 2026Article
- Copper and Nitrogen Co-doped Fluorescent Carbon Quantum Dots as a Fluorescent ''turn-off" Sensor for Determination of Tetracyclines Antibiotics.Journal of fluorescence · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Chiral carbon dots (CDs) are gaining significant interest because of their potential uses in the biological fields. The biological effects of these nanoparticles are highly influenced by their chiral structure. The influence of CD's chirality on cell imaging with red emission, particularly in both fixed and live cell states, has not been studied yet. Here, red emissive chiral CDs (LCD and DCD) were prepared through a simple and one-step method by tyrosine (L and D) and phenylenediamine (ortho). The LCD and DCD share very identical properties, including optical absorption, fluorescence emission, functional groups, size, and zeta potential, with the only difference being their chirality. Red emission minimizes tissue auto-fluorescence interference and enhances tissue penetration depth, making these CDs ideal for cell imaging. As staining agents, LCDs effectively enter cells and predominantly localize in the cytoplasm and nucleolus but the brightness of DCD is lower than LCDs and is not able to identify nucleoli. In addition, both LCDs and DCDs are highly biocompatible, but LCDs exhibit much lower toxicity. DCDs show significant toxicity from 20 µg.mL
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