Evidence map›Paper›PMID 40240172›Full record

ArticleEndocrine journal2025

Association between total bilirubin and sarcopenia in people with type 2 diabetes: The KAMOGAWA-A study.

Shinta Yamamoto, Hiroshi Okada, Natsuko Shinagawa, Nozomi Kuramoto, Yuriko Ono, Megumi Minamida, Junya Hironaka, Chihiro Munekawa, Yuka Hasegawa, Hanako Nakajima and 12 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Endocrine journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors.

Shinta YamamotoDepartment of Endocrinology and Metabolism, Kyoto Prefectural University of Medicine, Graduate School of Medical Science, Kyoto, Japan.ORCID http://orcid.org/0009-0001-5617-7978
Hiroshi OkadaDepartment of Endocrinology and Metabolism, Kyoto Prefectural University of Medicine, Graduate School of Medical Science, Kyoto, Japan.ORCID http://orcid.org/0000-0002-1707-970X
Natsuko ShinagawaDepartment of Endocrinology and Metabolism, Kyoto Prefectural University of Medicine, Graduate School of Medical Science, Kyoto, Japan.
Nozomi KuramotoDepartment of Endocrinology and Metabolism, Kyoto Prefectural University of Medicine, Graduate School of Medical Science, Kyoto, Japan.
Yuriko OnoDepartment of Endocrinology and Metabolism, Kyoto Prefectural University of Medicine, Graduate School of Medical Science, Kyoto, Japan.
Megumi MinamidaDepartment of Endocrinology and Metabolism, Kyoto Prefectural University of Medicine, Graduate School of Medical Science, Kyoto, Japan.
Junya HironakaDepartment of Endocrinology and Metabolism, Kyoto Prefectural University of Medicine, Graduate School of Medical Science, Kyoto, Japan.ORCID http://orcid.org/0000-0002-2970-5333
Chihiro MunekawaDepartment of Endocrinology and Metabolism, Kyoto Prefectural University of Medicine, Graduate School of Medical Science, Kyoto, Japan.ORCID http://orcid.org/0000-0001-9603-1802
Yuka HasegawaDepartment of Endocrinology and Metabolism, Kyoto Prefectural University of Medicine, Graduate School of Medical Science, Kyoto, Japan.ORCID http://orcid.org/0000-0003-3435-6868
Hanako NakajimaDepartment of Endocrinology and Metabolism, Kyoto Prefectural University of Medicine, Graduate School of Medical Science, Kyoto, Japan.ORCID http://orcid.org/0000-0002-3209-1790
Nobuko KitagawaDepartment of Endocrinology and Metabolism, Kyoto Prefectural University of Medicine, Graduate School of Medical Science, Kyoto, Japan.ORCID http://orcid.org/0000-0001-6624-0101
Takuro OkamuraDepartment of Endocrinology and Metabolism, Kyoto Prefectural University of Medicine, Graduate School of Medical Science, Kyoto, Japan.ORCID http://orcid.org/0000-0001-7269-1697
Yoshitaka HashimotoDepartment of Diabetes and Endocrinology, Matsushita Memorial Hospital, Moriguchi, Japan.ORCID http://orcid.org/0000-0002-8794-0550
Takafumi OsakaDepartment of Endocrinology and Metabolism, Kyoto Prefectural University of Medicine, Graduate School of Medical Science, Kyoto, Japan.ORCID http://orcid.org/0000-0002-2025-2518
Noriyuki KitagawaDepartment of Diabetology, Kameoka Municipal Hospital, Kameoka, Japan.ORCID http://orcid.org/0000-0003-3263-9469
Rieko NakataniDepartment of Endocrinology and Metabolism, Kyoto Prefectural University of Medicine, Graduate School of Medical Science, Kyoto, Japan.
Saori MajimaDepartment of Endocrinology and Metabolism, Kyoto Prefectural University of Medicine, Graduate School of Medical Science, Kyoto, Japan.
Takafumi SenmaruDepartment of Endocrinology and Metabolism, Kyoto Prefectural University of Medicine, Graduate School of Medical Science, Kyoto, Japan.ORCID http://orcid.org/0000-0001-5883-0216
Emi UshigomeDepartment of Endocrinology and Metabolism, Kyoto Prefectural University of Medicine, Graduate School of Medical Science, Kyoto, Japan.ORCID http://orcid.org/0000-0003-1031-4380
Naoko NakanishiDepartment of Endocrinology and Metabolism, Kyoto Prefectural University of Medicine, Graduate School of Medical Science, Kyoto, Japan.ORCID http://orcid.org/0000-0003-0092-2593
Masahide HamaguchiDepartment of Endocrinology and Metabolism, Kyoto Prefectural University of Medicine, Graduate School of Medical Science, Kyoto, Japan.ORCID http://orcid.org/0000-0002-8651-4445
Michiaki FukuiDepartment of Endocrinology and Metabolism, Kyoto Prefectural University of Medicine, Graduate School of Medical Science, Kyoto, Japan.ORCID http://orcid.org/0000-0003-0903-1797

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bilirubin is associated with vascular complications in diabetes. However, the correlation between bilirubin and sarcopenia or muscle strength has not been investigated. This study aimed to investigate the association between total bilirubin and skeletal muscle mass index (SMI), hand grip strength (HGS), and sarcopenia in patients with type 2 diabetes. This cross-sectional study included 1,108 patients with type 2 diabetes from three hospitals in Japan. Multiple and logistic regression analyses were used to examine the relationships between total bilirubin and SMI, HGS, and sarcopenia. Of the participants, 473 (43%) were women. The median (interquartile range) age, and glycated hemoglobin were 67 (59-73) years, and 7.4 (6.7-8.6) %, respectively. The median SMIs for women and men were 6.32 (5.73-7.04) kg/m

Indexed as

BilirubinDiabetes Mellitus, Type 2SarcopeniaAgedCross-Sectional StudiesFemaleHand StrengthHumansJapanMaleMiddle AgedMuscle, SkeletalBilirubinMuscle massMuscle strengthSarcopeniaTotal bilirubinType2 diabetes

Identifiers

PMID40240172
PMCPMC12340250

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.