ArticleEuropean journal of dentistry2025
Biodegradation, Angiogenesis, and Inflammatory Response of a Collagen-Chitosan-Polyvinyl Alcohol (PVA) Membrane: In Vivo Model of Guided Tissue Regeneration.
Article in European journal of dentistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
The aim of this study was to examine the biodegradation, angiogenesis, and inflammatory response in collagen-chitosan-polyvinyl alcohol (PVA) membranes.This study employed an experimental approach utilizing a randomized controlled trial design. Wistar rats were used as subjects, with 51 rats divided into three groups. Each group received a different treatment: application of the collagen-chitosan-PVA membrane, pericardial membrane, or cross-linked pericardial membrane, administered subcutaneously. On days 0, 7, 14, and 30, the rats were terminated, and the membranes and surrounding tissues were collected for analysis. A histological examination was performed to evaluate the membrane biodegradation rate, the number of blood vessels formed, and the inflammatory response.The data were analyzed using the Kruskal-Wallis and Mann-Whitney tests, with a
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