Evidence map›Paper›PMID 40239678›Full record

ArticleJournal of radiological protection : official journal of the Society for Radiological Protection2025

Colossus: software for radiation epidemiological studies with big data.

Eric Giunta, Dawson Stutzman, Sarah S Cohen, Benjamin French, Linda Walsh, Lawrence T Dauer, John D Boice, Steve R Blattnig, Dan Andresen, Amir A Bahadori

Abstract read
In one paragraph

Article in Journal of radiological protection : official journal of the Society for Radiological Protection, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Eric GiuntaKansas State University, Manhattan, KS, United States of America.ORCID 0000-0002-1577-766X
Dawson StutzmanKansas State University, Manhattan, KS, United States of America.
Sarah S CohenDLH Corporation, Atlanta, GA, United States of America.ORCID 0000-0003-0421-1983
Benjamin FrenchVanderbilt University Medical Center, Nashville, TN, United States of America.
Linda WalshUniversity of Zürich, Zürich, Switzerland.
Lawrence T DauerMemorial Sloan Kettering Cancer Center, New York City, NY, United States of America.ORCID 0000-0002-5629-8462
John D BoiceVanderbilt University Medical Center, Nashville, TN, United States of America.ORCID 0000-0002-8755-1299
Steve R BlattnigNASA Langley Research Center, Hampton, VA, United States of America.ORCID 0000-0002-8449-1024
Dan AndresenKansas State University, Manhattan, KS, United States of America.ORCID 0000-0003-2345-6695
Amir A BahadoriKansas State University, Manhattan, KS, United States of America.ORCID 0000-0002-4589-105X

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Hongbiao Carl Lekaye · 1985 to 2026
$347.4M
The role of prestimulus oscillatory brain dynamics in auditory memoryP20GM113109 · NIGMS · KANSAS STATE UNIVERSITY · PI Maria Magdalena Diehl · 2017 to 2026
$24.1M
National Science Foundation ACI-1440548National Science Foundation CHE-1726332National Science Foundation CNS-1006860National Science Foundation EPS-0919443National Science Foundation EPS-1006860NCI NIH HHS P30 CA008748NIGMS NIH HHS P20 GM113109
6 · The paper itself

Abstract

Colossus is designed to meet a growing need for survival analysis software capable of analyzing tens of millions of rows of radiation epidemiological data. Colossus is an R package devised to offer scalable survival analysis for the Million Person Study. The total and relative rate equations available in Colossus are outlined in this article, which are used in conjunction with Cox proportional hazards, Poisson, and Fine-Grey regression models. Following a comparison with existing software, validation with epidemiological cohort data is described. Exposure data and specific causes of death among workers at Los Alamos National Laboratory and U.S. nuclear power plants were analyzed by Colossus and 32-bit Epicure and compared with published results. Colossus results agreed with the results of existing software and previous publications.

Indexed as

Big DataOccupational ExposureSoftwareEpidemiologic StudiesHumansNuclear Power PlantsSurvival Analysisbig dataCox proportional hazardMillion Person StudyPoisson regressionradiation epidemiology

Identifiers

PMID40239678
PMCPMC13112907

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.